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000861567 1001_ $$00000-0002-0173-6090$$aChen, Zhaolin$$b0$$eCorresponding author
000861567 245__ $$aFrom simultaneous to synergistic MR-PET brain imaging: A review of hybrid MR-PET imaging methodologies
000861567 260__ $$aNew York, NY$$bWiley-Liss$$c2018
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000861567 520__ $$aSimultaneous Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) scanning is a recent major development in biomedical imaging. The full integration of the PET detector ring and electronics within the MR system has been a technologically challenging design to develop but provides capacity for simultaneous imaging and the potential for new diagnostic and research capability. This article reviews state‐of‐the‐art MR‐PET hardware and software, and discusses future developments focusing on neuroimaging methodologies for MR‐PET scanning. We particularly focus on the methodologies that lead to an improved synergy between MRI and PET, including optimal data acquisition, PET attenuation and motion correction, and joint image reconstruction and processing methods based on the underlying complementary and mutual information. We further review the current and potential future applications of simultaneous MR‐PET in both systems neuroscience and clinical neuroimaging research. We demonstrate a simultaneous data acquisition protocol to highlight new applications of MR‐PET neuroimaging research studies.
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000861567 7001_ $$00000-0001-7222-7181$$aJamadar, Sharna D.$$b1
000861567 7001_ $$00000-0003-3021-3026$$aLi, Shenpeng$$b2
000861567 7001_ $$00000-0003-2011-9394$$aSforazzini, Francesco$$b3
000861567 7001_ $$00000-0002-4946-3837$$aBaran, Jakub$$b4
000861567 7001_ $$0P:(DE-HGF)0$$aFerris, Nicholas$$b5
000861567 7001_ $$0P:(DE-Juel1)131794$$aShah, N. J.$$b6$$ufzj
000861567 7001_ $$00000-0002-3186-4026$$aEgan, Gary F.$$b7
000861567 773__ $$0PERI:(DE-600)1492703-2$$a10.1002/hbm.24314$$gVol. 39, no. 12, p. 5126 - 5144$$n12$$p5126 - 5144$$tHuman brain mapping$$v39$$x1065-9471$$y2018
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