% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Wyss:861573,
      author       = {Wyss, Christine and Tse, Desmond H Y and Boers, Frank and
                      Shah, N. J. and Neuner, Irene and Kawohl, Wolfram},
      title        = {{A}ssociation between {C}ortical {GABA} and {L}oudness
                      {D}ependence of {A}uditory {E}voked {P}otentials ({LDAEP})
                      in {H}umans},
      journal      = {The international journal of neuropsychopharmacology},
      volume       = {21},
      number       = {9},
      issn         = {1469-5111},
      address      = {Oxford},
      publisher    = {Oxford Univ. Press},
      reportid     = {FZJ-2019-02024},
      pages        = {809 - 813},
      year         = {2018},
      abstract     = {Loudness dependence of auditory evoked potentials (LDAEP)
                      is a widely used EEG-based biomarker for central
                      serotonergic activity. Serotonin has been shown to be
                      associated with different psychiatric disorders such as
                      depression and schizophrenia. Despite its clinical
                      significance, the underlying neurochemical mechanism of this
                      promising marker is not fully understood, and further
                      research is needed to improve its validity. Other
                      neurotransmitters might have a significant impact on this
                      measure. Thus, we assessed the inhibitory action through
                      individual GABA/H20 concentrations and GABA/glutamate ratios
                      by means of magnetic resonance spectroscopy at 3T in healthy
                      subjects. The measurements were assessed in the primary
                      auditory cortex to investigate the association with the
                      LDAEP, whose generators are mainly in the primary auditory
                      cortex. For the first time, this study examines the link
                      between GABAergic neurotransmission and LDAEP, and the data
                      preliminary show that GABA may not contribute to the
                      generation of EEG-based LDAEP.},
      cin          = {INM-4 / INM-11 / JARA-BRAIN},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-4-20090406 / I:(DE-Juel1)INM-11-20170113 /
                      $I:(DE-82)080010_20140620$},
      pnm          = {573 - Neuroimaging (POF3-573)},
      pid          = {G:(DE-HGF)POF3-573},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:29917080},
      UT           = {WOS:000446178200003},
      doi          = {10.1093/ijnp/pyy056},
      url          = {https://juser.fz-juelich.de/record/861573},
}