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@ARTICLE{Zhang:861679,
      author       = {Zhang, Ke and Sturm, Volker J. and Buschle, Lukas R. and
                      Hahn, Artur and Yun, Seong Dae and Shah, N. J. and Bendszus,
                      Martin and Heiland, Sabine and Schlemmer, Heinz-Peter and
                      Ziener, Christian H. and Kurz, Felix T.},
      title        = {{D}ual-contrast p{CASL} using simultaneous
                      gradient-echo/spin-echo multiband {EPI}},
      journal      = {Magnetic resonance imaging},
      volume       = {57},
      issn         = {0730-725X},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {FZJ-2019-02116},
      pages        = {359 - 367},
      year         = {2019},
      abstract     = {A 2D gradient-echo EPI is commonly employed for arterial
                      spin labeling (ASL) readout to achieve fast whole brain
                      coverage measurements. However, such a readout suffers from
                      susceptibility artifacts induced by magnetic field
                      inhomogeneities. To reduce these susceptibility effects,
                      single–shot spin-echo EPI was proposed to be used for
                      acquisitions in continuous ASL (CASL). To minimize
                      functional and physiological variations, a gradient-echo
                      (GE)/spin-echo (SE) dual-echo EPI readout of the CASL
                      sequence is needed for a comparison between GE- and SE-based
                      determination of cerebral blood flow (CBF). In this study,
                      we employed a simultaneous GE/SE multiband EPI as the
                      readout of a pseudo-CASL (pCASL) sequence. Motor cortex
                      activations derived from a finger-tapping task and
                      functional networks from resting state fMRI were compared
                      for both GE and SE contrasts. Direct comparison of SE and GE
                      contrasts revealed that GE ASL provides an improved
                      sensitivity of functional activity in finger-tapping and in
                      resting-state imaging. SE ASL, on the other hand, suffered
                      less from susceptibility artifacts induced by magnetic field
                      inhomogeneities and pulsatile flow artifacts.},
      cin          = {INM-4 / INM-11 / JARA-BRAIN},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-4-20090406 / I:(DE-Juel1)INM-11-20170113 /
                      $I:(DE-82)080010_20140620$},
      pnm          = {573 - Neuroimaging (POF3-573)},
      pid          = {G:(DE-HGF)POF3-573},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:30500347},
      UT           = {WOS:000458096100041},
      doi          = {10.1016/j.mri.2018.11.018},
      url          = {https://juser.fz-juelich.de/record/861679},
}