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@ARTICLE{Li:862045,
author = {Li, Changhong and Fronczek‐Poncelet, Judith and Lange,
Denise and Hennecke, Eva and Kroll, Tina and Matusch,
Andreas and Aeschbach, Daniel and Bauer, Andreas and
Elmenhorst, Eva‐Maria and Elmenhorst, David},
title = {{I}mpact of acute sleep deprivation on dynamic functional
connectivity states},
journal = {Human brain mapping},
volume = {41},
number = {4},
issn = {1047-3211},
address = {New York, NY},
publisher = {Wiley-Liss},
reportid = {FZJ-2019-02411},
pages = {994-1005},
year = {2020},
abstract = {Sleep deprivation (SD) could amplify the temporal
fluctuation of spontaneous brain activities that reflect
different arousal levels using a dynamic functional
connectivity (dFC) approach. Therefore, we intended to
evaluate the test–retest reliability of dFC
characteristics during rested wakefulness (RW), and to
explore how the properties of these dynamic connectivity
states were affected by extended durations of acute sleep
loss (28/52 hr). We acquired resting‐state fMRI and
neuropsychological datasets in two independent studies: (a)
twice during RW and once after 28 hr of SD (n = 15) and (b)
after 52 hr of SD and after 14 hr of recovery sleep (RS; n =
14). Sliding‐window correlations approach was applied to
estimate their covariance matrices and corresponding three
connectivity states were generated. The test–retest
reliability of dFC properties demonstrated mean dwell time
and fraction of connectivity states were reliable. After SD,
the mean dwell time of a specific state, featured by strong
subcortical–cortical anticorrelations, was significantly
increased. Conversely, another globally hypoconnected state
was significantly decreased. Subjective sleepiness and
objective performances were separately positive and negative
correlated with the increased and decreased state. Two brain
connectivity states and their alterations might be
sufficiently sensitive to reflect changes in the dynamics of
brain mental activities after sleep loss.},
cin = {INM-2},
ddc = {610},
cid = {I:(DE-Juel1)INM-2-20090406},
pnm = {573 - Neuroimaging (POF3-573) / 571 - Connectivity and
Activity (POF3-571) / 572 - (Dys-)function and Plasticity
(POF3-572)},
pid = {G:(DE-HGF)POF3-573 / G:(DE-HGF)POF3-571 /
G:(DE-HGF)POF3-572},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:31680379},
UT = {WOS:000493799800001},
doi = {10.1002/hbm.24855},
url = {https://juser.fz-juelich.de/record/862045},
}