%0 Journal Article
%A Werner, Jan-Michael
%A Brunn, Anna
%A Fink, Gereon Rudolf
%A Galldiks, Norbert
%T Magnetic Resonance Imaging Reveals a Pronounced Treatment Response of a Isocitrate Dehydrogenase− and B-Raf Proto-Oncogene−Wildtype Epithelioid Glioblastoma
%J World neurosurgery
%V 127
%@ 1878-8750
%C Amsterdam
%I Elsevier
%M FZJ-2019-02683
%P 213-215
%D 2019
%X We here report findings on magnetic resonance imaging from a 60-year-old patient with an epithelioid glioblastoma of the corpus callosum treated with radiotherapy in combination with concomitant and adjuvant temozolomide. Neuropathology revealed a highly aggressive molecular subtype of the epithelioid glioblastoma without an isocitrate dehydrogenase and B-Raf proto-oncogene mutation or a O6-methylguanine-DNA-methyltransferase promoter hypermethylation. This subtype is typically associated with an unfavorable clinical course and poor overall survival. Unexpectedly, the first follow-up magnetic resonance imaging 10 weeks after chemoradiation completion revealed an early and almost complete treatment response
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:30974270
%U <Go to ISI:>//WOS:000473128300197
%R 10.1016/j.wneu.2019.04.025
%U https://juser.fz-juelich.de/record/862349