TY  - JOUR
AU  - Werner, Jan-Michael
AU  - Brunn, Anna
AU  - Fink, Gereon Rudolf
AU  - Galldiks, Norbert
TI  - Magnetic Resonance Imaging Reveals a Pronounced Treatment Response of a Isocitrate Dehydrogenase− and B-Raf Proto-Oncogene−Wildtype Epithelioid Glioblastoma
JO  - World neurosurgery
VL  - 127
SN  - 1878-8750
CY  - Amsterdam
PB  - Elsevier
M1  - FZJ-2019-02683
SP  - 213-215
PY  - 2019
AB  - We here report findings on magnetic resonance imaging from a 60-year-old patient with an epithelioid glioblastoma of the corpus callosum treated with radiotherapy in combination with concomitant and adjuvant temozolomide. Neuropathology revealed a highly aggressive molecular subtype of the epithelioid glioblastoma without an isocitrate dehydrogenase and B-Raf proto-oncogene mutation or a O6-methylguanine-DNA-methyltransferase promoter hypermethylation. This subtype is typically associated with an unfavorable clinical course and poor overall survival. Unexpectedly, the first follow-up magnetic resonance imaging 10 weeks after chemoradiation completion revealed an early and almost complete treatment response
LB  - PUB:(DE-HGF)16
C6  - pmid:30974270
UR  - <Go to ISI:>//WOS:000473128300197
DO  - DOI:10.1016/j.wneu.2019.04.025
UR  - https://juser.fz-juelich.de/record/862349
ER  -