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@ARTICLE{Werner:862349,
author = {Werner, Jan-Michael and Brunn, Anna and Fink, Gereon Rudolf
and Galldiks, Norbert},
title = {{M}agnetic {R}esonance {I}maging {R}eveals a {P}ronounced
{T}reatment {R}esponse of a {I}socitrate {D}ehydrogenase−
and {B}-{R}af {P}roto-{O}ncogene−{W}ildtype {E}pithelioid
{G}lioblastoma},
journal = {World neurosurgery},
volume = {127},
issn = {1878-8750},
address = {Amsterdam},
publisher = {Elsevier},
reportid = {FZJ-2019-02683},
pages = {213-215},
year = {2019},
abstract = {We here report findings on magnetic resonance imaging from
a 60-year-old patient with an epithelioid glioblastoma of
the corpus callosum treated with radiotherapy in combination
with concomitant and adjuvant temozolomide. Neuropathology
revealed a highly aggressive molecular subtype of the
epithelioid glioblastoma without an isocitrate dehydrogenase
and B-Raf proto-oncogene mutation or a
O6-methylguanine-DNA-methyltransferase promoter
hypermethylation. This subtype is typically associated with
an unfavorable clinical course and poor overall survival.
Unexpectedly, the first follow-up magnetic resonance imaging
10 weeks after chemoradiation completion revealed an early
and almost complete treatment response},
cin = {INM-3},
ddc = {610},
cid = {I:(DE-Juel1)INM-3-20090406},
pnm = {572 - (Dys-)function and Plasticity (POF3-572)},
pid = {G:(DE-HGF)POF3-572},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:30974270},
UT = {WOS:000473128300197},
doi = {10.1016/j.wneu.2019.04.025},
url = {https://juser.fz-juelich.de/record/862349},
}