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| Home > Publications database > Magnetic Resonance Imaging Reveals a Pronounced Treatment Response of a Isocitrate Dehydrogenase− and B-Raf Proto-Oncogene−Wildtype Epithelioid Glioblastoma > print |
| Home > Publications database > Magnetic Resonance Imaging Reveals a Pronounced Treatment Response of a Isocitrate Dehydrogenase− and B-Raf Proto-Oncogene−Wildtype Epithelioid Glioblastoma > print |
| 001 | 862349 | ||
| 005 | 20210130001310.0 | ||
| 024 | 7 | _ | |a 10.1016/j.wneu.2019.04.025 |2 doi |
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| 100 | 1 | _ | |a Werner, Jan-Michael |0 P:(DE-HGF)0 |b 0 |
| 245 | _ | _ | |a Magnetic Resonance Imaging Reveals a Pronounced Treatment Response of a Isocitrate Dehydrogenase− and B-Raf Proto-Oncogene−Wildtype Epithelioid Glioblastoma |
| 260 | _ | _ | |a Amsterdam |c 2019 |b Elsevier |
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| 520 | _ | _ | |a We here report findings on magnetic resonance imaging from a 60-year-old patient with an epithelioid glioblastoma of the corpus callosum treated with radiotherapy in combination with concomitant and adjuvant temozolomide. Neuropathology revealed a highly aggressive molecular subtype of the epithelioid glioblastoma without an isocitrate dehydrogenase and B-Raf proto-oncogene mutation or a O6-methylguanine-DNA-methyltransferase promoter hypermethylation. This subtype is typically associated with an unfavorable clinical course and poor overall survival. Unexpectedly, the first follow-up magnetic resonance imaging 10 weeks after chemoradiation completion revealed an early and almost complete treatment response |
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| 773 | _ | _ | |a 10.1016/j.wneu.2019.04.025 |g p. S1878875019310174 |0 PERI:(DE-600)2530041-6 |p 213-215 |t World neurosurgery |v 127 |y 2019 |x 1878-8750 |
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