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@ARTICLE{Caldeira:862629,
      author       = {Caldeira, Liliana and Rota Kops, Elena and Yun, Seong Dae
                      and da Silva, Nuno and Mauler, Jorg and Weirich, Christoph
                      and Scheins, Jurgen and Herzog, Hans and Tellmann, Lutz and
                      Lohmann, Philipp and Langen, Karl-Josef and Lerche,
                      Christoph and Shah, N. J.},
      title        = {{T}he {J}ülich {E}xperience {W}ith {S}imultaneous 3{T}
                      {MR}-{B}rain{PET}: {M}ethods and {T}echnology},
      journal      = {IEEE transactions on radiation and plasma medical sciences},
      volume       = {3},
      number       = {3},
      issn         = {2469-7303},
      address      = {New York, NY},
      publisher    = {IEEE},
      reportid     = {FZJ-2019-02891},
      pages        = {352 - 362},
      year         = {2019},
      abstract     = {Building on the success of positron emission tomography
                      (PET)/CT scanners, a hybrid imaging technology, combining
                      PET with the versatile attributes of magnetic resonance
                      imaging (MRI), has been in use for over ten years. At the
                      Forschungszentrum Jülich, one of the four prototypes
                      available worldwide, combining a commercial 3T MRI with a
                      newly developed BrainPET insert, was installed in 2008,
                      allowing simultaneous data acquisition with PET and MRI.
                      Here, we report on our ten-year-long experience of the
                      methods and technology developed through this paper with
                      numerous patients and volunteers. In the course of our
                      research, a number of different radiotracers, such as [ 18
                      F]Fluoroethyltyrosine, [ 11 C]Flumazenil, [ 11 C]Raclopride,
                      and [ 15 O]H 2 O, have been applied while simultaneously
                      measuring several different MR sequences. The PET data
                      obtained with the BrainPET has demonstrated higher image
                      quality and superior resolution capability compared to the
                      stand-alone PET scanner, ECAT Exact HR+. Furthermore, the
                      simultaneous acquisition of MR images alongside BrainPET
                      scans, using different sequences, showed an excellent
                      quality without any relevant artifacts and provided useful
                      complementary information. Our experiences with the hybrid
                      3T MR-BrainPET indicate a promising basis for further
                      developments of this unique technique, allowing simultaneous
                      brain imaging in a clinical setting.},
      cin          = {INM-11 / INM-4 / JARA-BRAIN},
      ddc          = {624},
      cid          = {I:(DE-Juel1)INM-11-20170113 / I:(DE-Juel1)INM-4-20090406 /
                      $I:(DE-82)080010_20140620$},
      pnm          = {573 - Neuroimaging (POF3-573)},
      pid          = {G:(DE-HGF)POF3-573},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000467062000012},
      doi          = {10.1109/TRPMS.2018.2863953},
      url          = {https://juser.fz-juelich.de/record/862629},
}