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@ARTICLE{Gleeson:863462,
author = {Gleeson, Padraig and Cantarelli, Matteo and Marin, Boris
and Quintana, Adrian and Earnshaw, Matt and Sadeh, Sadra and
Piasini, Eugenio and Birgiolas, Justas and Cannon, Robert C.
and Cayco-Gajic, N. Alex and Crook, Sharon and Davison,
Andrew P. and Dura-Bernal, Salvador and Ecker, András and
Hines, Michael L. and Idili, Giovanni and Lanore, Frederic
and Larson, Stephen D. and Lytton, William W. and Majumdar,
Amitava and McDougal, Robert A. and Sivagnanam, Subhashini
and Solinas, Sergio and Stanislovas, Rokas and van Albada,
Sacha and van Geit, Werner and Silver, R. Angus},
title = {{O}pen {S}ource {B}rain: {A} {C}ollaborative {R}esource for
{V}isualizing, {A}nalyzing, {S}imulating, and {D}eveloping
{S}tandardized {M}odels of {N}eurons and {C}ircuits},
journal = {Neuron},
volume = {103},
number = {3},
issn = {0896-6273},
address = {New York, NY},
publisher = {Elsevier},
reportid = {FZJ-2019-03520},
pages = {395-411.e5},
year = {2019},
abstract = {Computational models are powerful tools for exploring the
properties of complex biological systems. In neuroscience,
data-driven models of neural circuits that span multiple
scales are increasingly being used to understand brain
function in health and disease. But their adoption and reuse
has been limited by the specialist knowledge required to
evaluate and use them. To address this, we have developed
Open Source Brain, a platform for sharing, viewing,
analyzing, and simulating standardized models from different
brain regions and species. Model structure and parameters
can be automatically visualized and their dynamical
properties explored through browser-based simulations.
Infrastructure and tools for collaborative interaction,
development, and testing are also provided. We demonstrate
how existing components can be reused by constructing new
models of inhibition-stabilized cortical networks that match
recent experimental results. These features of Open Source
Brain improve the accessibility, transparency, and
reproducibility of models and facilitate their reuse by the
wider community.},
cin = {INM-6 / IAS-6 / INM-10},
ddc = {610},
cid = {I:(DE-Juel1)INM-6-20090406 / I:(DE-Juel1)IAS-6-20130828 /
I:(DE-Juel1)INM-10-20170113},
pnm = {574 - Theory, modelling and simulation (POF3-574) / HBP
SGA1 - Human Brain Project Specific Grant Agreement 1
(720270) / HBP - The Human Brain Project (604102) / HBP -
Human Brain Project (284941)},
pid = {G:(DE-HGF)POF3-574 / G:(EU-Grant)720270 /
G:(EU-Grant)604102 / G:(EU-Grant)284941},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:31201122},
UT = {WOS:000479119400009},
doi = {10.1016/j.neuron.2019.05.019},
url = {https://juser.fz-juelich.de/record/863462},
}