TY  - JOUR
AU  - Doppler, Christopher E. J.
AU  - Meyer, Linda
AU  - Dovern, Anna
AU  - Stühmer-Beckh, Jaro
AU  - Weiss-Blankenhorn, Peter
AU  - Fink, Gereon R.
TI  - Differential Impact of Social and Monetary Reward on Procedural Learning and Consolidation in Aging and Its Structural Correlates
JO  - Frontiers in aging neuroscience
VL  - 11
SN  - 1663-4365
CY  - Lausanne
PB  - Frontiers Research Foundation
M1  - FZJ-2019-04020
SP  - 188
PY  - 2019
AB  - In young (n = 36, mean ± SD: 24.8 ± 4.5 years) and older (n = 34, mean ± SD: 65.1 ± 6.5 years) healthy participants, we employed a modified version of the Serial Reaction Time task to measure procedural learning (PL) and consolidation while providing monetary and social reward. Using voxel-based morphometry (VBM), we additionally determined the structural correlates of reward-related motor performance (RMP) and PL. Monetary reward had a beneficial effect on PL in the older subjects only. In contrast, social reward significantly enhanced PL in the older and consolidation in the young participants. VBM analyses revealed that motor performance related to monetary reward was associated with larger grey matter volume (GMV) of the left striatum in the young, and motor performance related to social reward with larger GMV of the medial orbitofrontal cortex in the older group. The differential effects of social reward in young (improved consolidation) and both social and monetary rewards in older (enhanced PL) healthy subjects point to the potential of rewards for interventions targeting aging-associated motor decline or stroke-induced motor deficits.
LB  - PUB:(DE-HGF)16
C6  - pmid:31417395
UR  - <Go to ISI:>//WOS:000477801900001
DO  - DOI:10.3389/fnagi.2019.00188
UR  - https://juser.fz-juelich.de/record/864150
ER  -