TY  - JOUR
AU  - Dafsari, Hormos Salimi
AU  - Dovern, Anna
AU  - Fink, Gereon R.
AU  - Weiss-Blankenhorn, Peter
TI  - Deficient body structural description contributes to apraxic end-position errors in imitation
JO  - Neuropsychologia
VL  - 133
SN  - 0028-3932
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - FZJ-2019-04021
SP  - 107150
PY  - 2019
AB  - Apraxia is a common cognitive deficit after left hemisphere (LH) stroke. It has been suggested that a disturbed representation of the human body underlies apraxic imitation deficits. Thus, we here tested the hypothesis that a deficient body structural description (BSD), i.e., a deficient representation of a body part's position (relative to a standard human body), contributes to apraxic end-position errors in imitation, while controlling for deficits in the semantic representation of the human body (body image, BI) and naming deficits.A quantitative pointing task to assess putative BSD deficits and an apraxia assessment, including imitation and pantomime tasks, were applied to 27 patients with LH stroke and 19 healthy subjects. While LH stroke patients without apraxia (n=15) did not differ from control subjects in their pointing performance, patients suffering from imitation apraxia (n=10) showed a differential deficit when pointing to body parts of other humans compared to object parts. Voxel-based lesion symptom mapping (VLSM) revealed an association of these differential pointing deficits (indicating a deficient BSD) with lesions in the angular gyrus of the left inferior parietal cortex.This first quantitative group study of BSD deficits in LH stroke patients supports the notion that apraxic end-position errors in imitation are – at least in part – due to a deficient coding of the position of human body parts.
LB  - PUB:(DE-HGF)16
C6  - pmid:31369744
UR  - <Go to ISI:>//WOS:000493915600002
DO  - DOI:10.1016/j.neuropsychologia.2019.107150
UR  - https://juser.fz-juelich.de/record/864151
ER  -