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@ARTICLE{Dafsari:864151,
author = {Dafsari, Hormos Salimi and Dovern, Anna and Fink, Gereon R.
and Weiss-Blankenhorn, Peter},
title = {{D}eficient body structural description contributes to
apraxic end-position errors in imitation},
journal = {Neuropsychologia},
volume = {133},
issn = {0028-3932},
address = {Amsterdam [u.a.]},
publisher = {Elsevier Science},
reportid = {FZJ-2019-04021},
pages = {107150},
year = {2019},
abstract = {Apraxia is a common cognitive deficit after left hemisphere
(LH) stroke. It has been suggested that a disturbed
representation of the human body underlies apraxic imitation
deficits. Thus, we here tested the hypothesis that a
deficient body structural description (BSD), i.e., a
deficient representation of a body part's position (relative
to a standard human body), contributes to apraxic
end-position errors in imitation, while controlling for
deficits in the semantic representation of the human body
(body image, BI) and naming deficits.A quantitative pointing
task to assess putative BSD deficits and an apraxia
assessment, including imitation and pantomime tasks, were
applied to 27 patients with LH stroke and 19 healthy
subjects. While LH stroke patients without apraxia (n=15)
did not differ from control subjects in their pointing
performance, patients suffering from imitation apraxia
(n=10) showed a differential deficit when pointing to body
parts of other humans compared to object parts. Voxel-based
lesion symptom mapping (VLSM) revealed an association of
these differential pointing deficits (indicating a deficient
BSD) with lesions in the angular gyrus of the left inferior
parietal cortex.This first quantitative group study of BSD
deficits in LH stroke patients supports the notion that
apraxic end-position errors in imitation are – at least in
part – due to a deficient coding of the position of human
body parts.},
cin = {INM-3},
ddc = {610},
cid = {I:(DE-Juel1)INM-3-20090406},
pnm = {572 - (Dys-)function and Plasticity (POF3-572)},
pid = {G:(DE-HGF)POF3-572},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:31369744},
UT = {WOS:000493915600002},
doi = {10.1016/j.neuropsychologia.2019.107150},
url = {https://juser.fz-juelich.de/record/864151},
}