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000864465 1001_ $$0P:(DE-Juel1)165893$$aMechsner, Bastian$$b0
000864465 245__ $$aEnantioselective total synthesis of altersolanol A and N
000864465 260__ $$aAmsterdam [u.a.]$$bElsevier$$c2019
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000864465 520__ $$aThe development of the first enantioselective total synthesis of altersolanol N is reported. The decisive step of the synthesis is the enantioselective formation of the tetrahydroanthraquinone nucleus by a [4 + 2]-cycloaddition in high yield and with excellent diastereo- and enantioselectivity (>95:5 dr and 95:5 er). In addition, a demanding selective monoacetylation of the OH group at the C-2 position was achieved: an epoxide ring opening with the participation of a neighbouring acetyl group could be established. The route proved to be an efficient alternative to also access enantiomerically pure altersolanol A.
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000864465 7001_ $$0P:(DE-Juel1)139024$$aBöse, Dietrich$$b1
000864465 7001_ $$0P:(DE-Juel1)169329$$aHogenkamp, Fabian$$b2
000864465 7001_ $$0P:(DE-HGF)0$$aLedermann, Nadia$$b3
000864465 7001_ $$0P:(DE-Juel1)132001$$aHartmann, Rudolf$$b4
000864465 7001_ $$0P:(DE-Juel1)165763$$aBochinsky, Kevin$$b5
000864465 7001_ $$0P:(DE-HGF)0$$aFrey, Wolfgang$$b6
000864465 7001_ $$0P:(DE-Juel1)128906$$aPietruszka, Jörg$$b7$$eCorresponding author
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