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@ARTICLE{Belitsky:865026,
author = {Belitsky, V. and Schütz, G. M.},
title = {{S}tationary {RNA} polymerase fluctuations during
transcription elongation},
journal = {Physical review / E},
volume = {99},
number = {1},
issn = {2470-0045},
address = {Woodbury, NY},
publisher = {Inst.},
reportid = {FZJ-2019-04591},
pages = {012405},
year = {2019},
abstract = {We study fluctuation effects of nonsteric molecular
interactions between RNA polymerase (RNAP) motors that move
simultaneously on the same DNA track during transcription
elongation. Based on a stochastic model that allows for the
exact analytical computation of the stationary distribution
of RNAPs as a function of their density, interaction
strength, nucleoside triphosphate concentration, and rate of
pyrophosphate release we predict an almost geometric headway
distribution of subsequent RNAP transcribing on the same DNA
segment. The localization length which characterizes the
decay of the headway distribution depends directly only the
average density of RNAP and the interaction strength, but
not on specific single-RNAP properties. Density correlations
are predicted to decay exponentially with the distance (in
units of DNA base pairs), with a correlation length that is
significantly shorter than the localization length.},
cin = {ICS-2},
ddc = {530},
cid = {I:(DE-Juel1)ICS-2-20110106},
pnm = {551 - Functional Macromolecules and Complexes (POF3-551)},
pid = {G:(DE-HGF)POF3-551},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:30780341},
UT = {WOS:000455062900010},
doi = {10.1103/PhysRevE.99.012405},
url = {https://juser.fz-juelich.de/record/865026},
}