TY  - JOUR
AU  - Galldiks, Norbert
AU  - Brunn, Anna
AU  - Fink, Gereon R.
AU  - Langen, Karl-Josef
TI  - Dynamic FET PET Imaging of a “Butterfly” IDH-Wildtype Anaplastic Astrocytoma
JO  - Clinical nuclear medicine
VL  - 44
IS  - 10
SN  - 0363-9762
CY  - [S.l.]
PB  - Ovid
M1  - FZJ-2019-04698
SP  - e581 - e582
PY  - 2019
AB  - A variety of neoplastic and nonneoplastic conditions involve the corpus callosum, which may result in a “butterfly” appearance on conventional MRI. Typically, that pattern shows a bilateral and heterogeneous contrast enhancement of the lesion, occasionally with central nonenhancing areas indicating intralesional necrosis. In contrast, anaplastic gliomas may show only minimal or even a lack of contrast enhancement on MRI. We here report neuroimaging findings in a 69-year-old man with a “butterfly” pattern on dynamic FET [O-(2-[18F]-fluoroethyl)-L-tyrosine] PET and the diagnosis of an anaplastic astrocytoma (WHO grade III; IDH-1/−2 wildtype, no 1p/19q co-deletion) but without typical MRI contrast enhancement.
LB  - PUB:(DE-HGF)16
C6  - pmid:31348085
UR  - <Go to ISI:>//WOS:000502264000007
DO  - DOI:10.1097/RLU.0000000000002740
UR  - https://juser.fz-juelich.de/record/865148
ER  -