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@ARTICLE{Niether:865234,
      author       = {Niether, Doreen and Wiegand, Simone},
      title        = {{T}hermophoresis of biological and biocompatible compounds
                      in aqueous solution},
      journal      = {Journal of physics / Condensed matter Condensed matter},
      volume       = {31},
      number       = {50},
      issn         = {1361-648X},
      address      = {Bristol},
      publisher    = {IOP Publ.80390},
      reportid     = {FZJ-2019-04765},
      pages        = {503003-},
      year         = {2019},
      abstract     = {With rising popularity of Microscale Thermophoresis for the
                      characterisation of protein-ligand binding reactions and
                      possible applications in microfluidic devices, there is a
                      growing interest in considering thermodiffusion in the
                      context of life sciences. But although the understanding of
                      thermodiffusion in non-polar mixtures has grown rapidly in
                      recent years, predictions for associated mixtures like
                      aqueous solutions remain challenging. This review aims to
                      give an overview of the literature on thermodiffusion in
                      aqueous systems, show the difficulties in theoretical
                      description that arise from the non-ideal behaviour of
                      water-mixtures, and highlight the relevance of
                      thermodiffusion in a biological context. We find that the
                      thermodiffusion in aqueous systems is dominated by
                      contributions from heat of transfer, hydrogen bond
                      interactions and charge effects. However, the separation of
                      these effects is often difficult, especially in case of
                      biological systems where a systematic exclusion of
                      contributions may not be feasible.},
      cin          = {ICS-3 / IEK-8},
      ddc          = {530},
      cid          = {I:(DE-Juel1)ICS-3-20110106 / I:(DE-Juel1)IEK-8-20101013},
      pnm          = {551 - Functional Macromolecules and Complexes (POF3-551)},
      pid          = {G:(DE-HGF)POF3-551},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31491783},
      UT           = {WOS:000504451800002},
      doi          = {10.1088/1361-648X/ab421c},
      url          = {https://juser.fz-juelich.de/record/865234},
}