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@ARTICLE{Scarpazza:865237,
      author       = {Scarpazza, Cristina and Lattanzi, Guido Maria and
                      Antoniades, Mathilde and Di Fabio, Fabio and Sartori,
                      Giuseppe and Eickhoff, Simon B. and McGuire, Philip and
                      Tognin, Stefania},
      title        = {{S}ystematic review and multi-modal meta-analysis of
                      magnetic resonance imaging findings in 22q11.2 deletion
                      syndrome: {I}s more evidence needed?},
      journal      = {Neuroscience $\&$ biobehavioral reviews},
      volume       = {107},
      issn         = {0149-7634},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {FZJ-2019-04768},
      pages        = {143 - 153},
      year         = {2019},
      abstract     = {22q11.2 deletion syndrome (DS) is considered to be the most
                      robust genetic model of psychosis. In the last decade, there
                      has been increased interest in the brain abnormalities
                      associated with these genetic changes. Most imaging findings
                      in this population come from small samples. This increases
                      the risk of reporting spurious effects that reflect the
                      idiosyncrasies of each study. Thus, the current work is
                      aimed at identifying whether there are spatially consistent
                      structural and functional brain abnormalities in individuals
                      with 22q11.2 DS through (i) a comprehensive label-based
                      systematic review and (ii) a coordinate-based meta-analysis
                      of magnetic resonance imaging studies. The systematic review
                      identified the frontal middle gyri, posterior cingulum,
                      right cuneus and bilateral precuneus as the most affected
                      regions. The meta-analysis revealed consistent abnormalities
                      in the bilateral inferior parietal lobe, right precuneus,
                      right superior temporal gyrus and posterior cingulate
                      cortex. This study provides an important starting point for
                      future research as it sheds light on possible genetically
                      determined psychosis susceptibility regions.},
      cin          = {INM-7},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-7-20090406},
      pnm          = {574 - Theory, modelling and simulation (POF3-574)},
      pid          = {G:(DE-HGF)POF3-574},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31493414},
      UT           = {WOS:000501388000014},
      doi          = {10.1016/j.neubiorev.2019.09.004},
      url          = {https://juser.fz-juelich.de/record/865237},
}