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@ARTICLE{Iashina:865920,
      author       = {Iashina, E. G. and Grigoriev, S. V.},
      title        = {{L}arge-{S}cale {S}tructure of {C}hromatin: {A} {F}ractal
                      {G}lobule or a {L}ogarithmic {F}ractal?},
      journal      = {Journal of experimental and theoretical physics},
      volume       = {129},
      number       = {3},
      issn         = {1090-6509},
      address      = {Heidelberg [u.a.]},
      publisher    = {Springer},
      reportid     = {FZJ-2019-05197},
      pages        = {455 - 458},
      year         = {2019},
      abstract     = {Two physical models are considered to describe the
                      large-scale structure of chromatin in the nucleus of a
                      biological cell in the interphase state: a fractal globule
                      model and a logarithmic fractal model. Based on the
                      classification of fractal objects developed by the
                      small-angle neutron scattering (SANS) method, it is shown
                      that the fractal globule model does not satisfy the
                      experimental data on small-angle neutron scattering by the
                      nuclei of biological cells. Conversely, the logarithmic
                      fractal model well describes the experimental data on SANS
                      and, hence, provides a good approximation to describe the
                      large-scale structure of chromatin. The logarithmic fractal
                      model predicts that the nuclear space is exactly half-filled
                      with chromatin, and the second half consists of
                      interchromatin voids filled with nucleoplasma in which
                      various nuclear processes occur. Thus, two opposing trends
                      are balanced in the structural organization of chromatin: an
                      increase in the surface area of chromatin in the cell
                      nucleus (accessibility to external agents) and a decrease in
                      the volume occupied by chromatin (compactness of the
                      nucleus).},
      cin          = {JCNS-FRM-II / JCNS-1 / MLZ},
      ddc          = {530},
      cid          = {I:(DE-Juel1)JCNS-FRM-II-20110218 /
                      I:(DE-Juel1)JCNS-1-20110106 / I:(DE-588b)4597118-3},
      pnm          = {6G15 - FRM II / MLZ (POF3-6G15) / 6G4 - Jülich Centre for
                      Neutron Research (JCNS) (POF3-623)},
      pid          = {G:(DE-HGF)POF3-6G15 / G:(DE-HGF)POF3-6G4},
      experiment   = {EXP:(DE-MLZ)KWS3-20140101},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000491494700017},
      doi          = {10.1134/S106377611908017X},
      url          = {https://juser.fz-juelich.de/record/865920},
}