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@ARTICLE{Grodzinsky:866309,
      author       = {Grodzinsky, Yosef and Deschamps, Isabelle and Pieperhoff,
                      Peter and Iannilli, Francesca and Agmon, Galit and
                      Loewenstein, Yonatan and Amunts, Katrin},
      title        = {{L}ogical negation mapped onto the brain},
      journal      = {Brain structure $\&$ function},
      volume       = {225},
      issn         = {1863-2661},
      address      = {Heidelberg},
      publisher    = {Springer},
      reportid     = {FZJ-2019-05468},
      pages        = {19-31},
      year         = {2020},
      abstract     = {High-level cognitive capacities that serve communication,
                      reasoning, and calculation are essential for finding our way
                      in the world. But whether and to what extent these complex
                      behaviors share the same neuronal substrate are still
                      unresolved questions. The present study separated the
                      aspects of logic from language and numerosity—mental
                      faculties whose distinctness has been debated for
                      centuries—and identified a new cytoarchitectonic area as
                      correlate for an operation involving logical negation. A
                      novel experimental paradigm that was implemented here in an
                      RT/fMRI study showed a single cluster of activity that
                      pertains to logical negation. It was distinct from clusters
                      that were activated by numerical comparison and from the
                      traditional language regions. The localization of this
                      cluster was described by a newly identified
                      cytoarchitectonic area in the left anterior insula,
                      ventro-medial to Broca’s region. We provide evidence for
                      the congruence between the histologically and functionally
                      defined regions on multiple measures. Its position in the
                      left anterior insula suggests that it functions as a
                      mediator between language and reasoning areas.},
      cin          = {INM-1},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-1-20090406},
      pnm          = {571 - Connectivity and Activity (POF3-571) / HBP SGA1 -
                      Human Brain Project Specific Grant Agreement 1 (720270) /
                      HBP SGA2 - Human Brain Project Specific Grant Agreement 2
                      (785907)},
      pid          = {G:(DE-HGF)POF3-571 / G:(EU-Grant)720270 /
                      G:(EU-Grant)785907},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31680213},
      UT           = {WOS:000493786300001},
      doi          = {10.1007/s00429-019-01975-w},
      url          = {https://juser.fz-juelich.de/record/866309},
}