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| Home > Publications database > Perfusion weighted imaging using combined gradient/spin echo EPIK: Brain tumour applications in hybrid MR-PET > print |
| 001 | 866644 | ||
| 005 | 20230111074221.0 | ||
| 024 | 7 | _ | |a 10.1002/hbm.24537 |2 doi |
| 024 | 7 | _ | |a 1065-9471 |2 ISSN |
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| 037 | _ | _ | |a FZJ-2019-05723 |
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| 100 | 1 | _ | |a Shah, N. J. |0 P:(DE-Juel1)131794 |b 0 |e Corresponding author |u fzj |
| 245 | _ | _ | |a Perfusion weighted imaging using combined gradient/spin echo EPIK: Brain tumour applications in hybrid MR-PET |
| 260 | _ | _ | |a New York, NY |c 2021 |b Wiley-Liss |
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| 520 | _ | _ | |a Advanced perfusion‐weighted imaging (PWI) methods that combine gradient echo (GE) and spin echo (SE) data are important tools for the study of brain tumours. In PWI, single‐shot, EPI‐based methods have been widely used due to their relatively high imaging speed. However, when used with increasing spatial resolution, single‐shot EPI methods often show limitations in whole‐brain coverage for multi‐contrast applications. To overcome this limitation, this work employs a new version of EPI with keyhole (EPIK) to provide five echoes: two with GEs, two with mixed GESE and one with SE; the sequence is termed “GESE‐EPIK.” The performance of GESE‐EPIK is evaluated against its nearest relative, EPI, in terms of the temporal signal‐to‐noise ratio (tSNR). Here, data from brain tumour patients were acquired using a hybrid 3T MR‐BrainPET scanner.GESE‐EPIK resulted in reduced susceptibility artefacts, shorter TEs for the five echoes and increased brain coverage when compared to EPI. Moreover, compared to EPI, EPIK achieved a comparable tSNR for the first and second echoes and significantly higher tSNR for other echoes.A new method to obtain multi‐echo GE and SE data with shorter TEs and increased brain coverage is demonstrated. As proposed here, the workflow can be shortened and the integration of multimodal clinical MR‐PET studies can be facilitated. |
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| 700 | 1 | _ | |a da Silva, Nuno André |0 P:(DE-Juel1)157838 |b 1 |
| 700 | 1 | _ | |a Yun, Seong Dae |0 P:(DE-Juel1)141899 |b 2 |
| 773 | _ | _ | |a 10.1002/hbm.24537 |0 PERI:(DE-600)1492703-2 |n 13 |p 4144-4154 |t Human brain mapping |v 42 |y 2021 |x 1065-9471 |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/866644/files/Manuscript.pdf |y OpenAccess |
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