% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Kanwar:867577,
      author       = {Kanwar, Rohini and Gradzielski, Michael and Prevost,
                      Sylvain and Appavou, Marie-Sousai and Mehta, S. K.},
      title        = {{E}xperimental validation of biocompatible nanostructured
                      lipid carriers of sophorolipid: {O}ptimization,
                      characterization and in-vitro evaluation},
      journal      = {Colloids and surfaces / B Biointerfaces B},
      volume       = {181},
      issn         = {0927-7765},
      address      = {[S.l.]},
      publisher    = {Science Direct},
      reportid     = {FZJ-2019-06200},
      pages        = {845 - 855},
      year         = {2019},
      abstract     = {To date, the potential of sophorolipids (an important class
                      of glycolipids) has been exploited solely as amphipathic
                      molecules but their ability to formulate lipid nanoparticles
                      has never been explored. In this report, for the first time,
                      lipid nanostructures coated with polysorbates (Tweens) were
                      formulated by a hot dispersion method. By varying the amount
                      of lipid, type of surfactant, and alcohol, dilution ratio
                      etc., the formulation was optimized with respect to its
                      stability, which is a central aspect of their potential
                      applications. Their comprehensive physicochemical
                      characterization was done using static and dynamic light
                      scattering (SLS, DLS), small angle neutron scattering
                      (SANS), zeta-potential, transmission electron microscopy
                      (TEM), scanning electron microscopy (SEM), and atomic force
                      microscopy (AFM) techniques. Further hemolysis study was
                      conducted to understand the in-vitro cytotoxicity levels of
                      the lipidic nanoparticles prior to its application as a
                      potent drug delivery device for countermanding the problems
                      associated with challenging tuberculosis and leprosy
                      drug-Rifampicin. Attaining high entrapment efficiency and
                      sustained release from the developed carrier, further
                      interaction with bovine serum albumin was investigated, to
                      understand the in-vivo behavior of the nanostructured lipid
                      carriers (NLCs).},
      cin          = {JCNS-FRM-II / JCNS-1 / MLZ},
      ddc          = {540},
      cid          = {I:(DE-Juel1)JCNS-FRM-II-20110218 /
                      I:(DE-Juel1)JCNS-1-20110106 / I:(DE-588b)4597118-3},
      pnm          = {6G4 - Jülich Centre for Neutron Research (JCNS) (POF3-623)
                      / 6G15 - FRM II / MLZ (POF3-6G15)},
      pid          = {G:(DE-HGF)POF3-6G4 / G:(DE-HGF)POF3-6G15},
      experiment   = {EXP:(DE-MLZ)KWS1-20140101},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31254745},
      UT           = {WOS:000481565300098},
      doi          = {10.1016/j.colsurfb.2019.06.036},
      url          = {https://juser.fz-juelich.de/record/867577},
}