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@ARTICLE{Langen:868117,
      author       = {Langen, Karl-Josef and Heinzel, Alexander and Lohmann,
                      Philipp and Mottaghy, Felix M. and Galldiks, Norbert},
      title        = {{A}dvantages and limitations of amino acid {PET} for
                      tracking therapy response in glioma patients},
      journal      = {Expert review of neurotherapeutics},
      volume       = {20},
      number       = {2},
      issn         = {1744-8360},
      address      = {Abingdon},
      publisher    = {Taylor $\&$ Francis Group},
      reportid     = {FZJ-2019-06704},
      pages        = {137-146},
      year         = {2020},
      abstract     = {Introduction: Today, magnetic resonance imaging (MRI) is
                      the standard method for monitoring patients with brain
                      tumors. The ability of conventional MRI in differentiating
                      neoplastic tissue from nonspecific, treatment-related
                      changes after surgery, radio-, chemo- or immunotherapy,
                      however, remains limited. Therefore, advanced MRI sequences
                      and positron emission tomography (PET) are increasingly
                      being considered to improve decision-making.Areas covered:
                      PET using radiolabeled amino acids has evolved into an
                      important diagnostic tool to overcome some of the
                      shortcomings of conventional MRI. In view of the rapidly
                      developing novel treatment strategies, a reliable statement
                      on the response to therapy is becoming increasingly
                      important. This article gives an overview of the current
                      results of PET with radiolabelled amino acids in therapy
                      monitoring of standard therapy as well as various innovative
                      approaches in the treatment of patients with cerebral
                      gliomas.Expert opinion: Amino acid PET has proven to be
                      helpful in therapy monitoring of gliomas, the costs are low
                      in relation to the costs of therapy and the clinical
                      benefit, and a widespread clinical use is highly desirable.},
      cin          = {INM-3 / INM-4},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-3-20090406 / I:(DE-Juel1)INM-4-20090406},
      pnm          = {572 - (Dys-)function and Plasticity (POF3-572)},
      pid          = {G:(DE-HGF)POF3-572},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31829748},
      UT           = {WOS:000503631900001},
      doi          = {10.1080/14737175.2020.1704256},
      url          = {https://juser.fz-juelich.de/record/868117},
}