guest ::
| Home > Publications database > Intermittent theta burst stimulation applied during early rehabilitation after stroke: study protocol for a randomised controlled trial > print |
| Home > Publications database > Intermittent theta burst stimulation applied during early rehabilitation after stroke: study protocol for a randomised controlled trial > print |
| 001 | 868434 | ||
| 005 | 20220930130226.0 | ||
| 024 | 7 | _ | |a 10.1136/bmjopen-2019-034088 |2 doi |
| 024 | 7 | _ | |a 2044-6055 |2 ISSN |
| 024 | 7 | _ | |a 2053-3624 |2 ISSN |
| 024 | 7 | _ | |a 2398-595X |2 ISSN |
| 024 | 7 | _ | |a 2128/23777 |2 Handle |
| 024 | 7 | _ | |a pmid:31892668 |2 pmid |
| 024 | 7 | _ | |a WOS:000512773400288 |2 WOS |
| 037 | _ | _ | |a FZJ-2020-00029 |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Hensel, Lukas |0 P:(DE-Juel1)142144 |b 0 |
| 245 | _ | _ | |a Intermittent theta burst stimulation applied during early rehabilitation after stroke: study protocol for a randomised controlled trial |
| 260 | _ | _ | |a London |c 2019 |b BMJ66930 |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1579763657_21215 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a ntroduction Intermittent theta burst stimulation (iTBS) applied to primary motor cortex (M1) has been shown to modulate both the excitability and connectivity of the motor system. A recent proof-of-principle study, based on a small group of hospitalised patients with acute ischemic stroke, suggested that iTBS applied to the ipsilesional M1 combined with physical therapy early after stroke can amplify motor recovery with lasting after effects. A randomised controlled clinical trial using a double-blind design is warranted to justify the implementation of iTBS-assisted motor rehabilitation in neurorehabilitation from an acute ischaemic stroke.Methods/design We investigate the effects of daily iTBS on early motor rehabilitation after stroke in an investigator-initiated, longitudinal randomised controlled trial. Patients (n=150) with hemiparesis receive either iTBS (600 pulses) applied to the ipsilesional motor cortex (M1) or a control stimulation (ie, coil placement over the parieto-occipital vertex in parallel to the interhemispheric fissure and with a tilt of 45°). On 8 consecutive workdays, a 45 min arm-centred motor training follows the intervention . The relative grip strength, defined as the grip force ratios of the affected and unaffected hands, serves as the primary outcome parameter. Secondary outcome parameters are measures of arm function (Action Research Arm Test, Fugl-Meyer Motor Scale), stroke severity (National Institutes of Health Stroke Scale), stroke-induced disability (modified Rankin Scale, Barthel Index), duration of inpatient rehabilitation, quality of life (EuroQol 5D), motor evoked potentials and the resting motor threshold of the ipsilesional M1.Ethics and dissemination The study was approved by the Ethics Commission of the Medical Faculty, University of Cologne, Germany (reference number 15-343). Data will be disseminated through peer-reviewed publications and presentations at conferences. Study title: Theta-Burst Stimulation in Early Rehabilitation after Stroke (acronym: TheSiReS). Study registration at German Registry for Clinical Trials (DRKS00008963) and at ClinicalTrials.gov (NCT02910024). |
| 536 | _ | _ | |a 572 - (Dys-)function and Plasticity (POF3-572) |0 G:(DE-HGF)POF3-572 |c POF3-572 |f POF III |x 0 |
| 588 | _ | _ | |a Dataset connected to CrossRef |
| 700 | 1 | _ | |a Grefkes, Christian |0 P:(DE-Juel1)161406 |b 1 |
| 700 | 1 | _ | |a Tscherpel, Caroline |0 P:(DE-HGF)0 |b 2 |
| 700 | 1 | _ | |a Ringmaier, Corinna |0 P:(DE-HGF)0 |b 3 |
| 700 | 1 | _ | |a Kraus, Daria |0 P:(DE-HGF)0 |b 4 |
| 700 | 1 | _ | |a Hamacher, Stefanie |0 P:(DE-HGF)0 |b 5 |
| 700 | 1 | _ | |a Volz, Lukas J |0 P:(DE-HGF)0 |b 6 |
| 700 | 1 | _ | |a Fink, Gereon R |0 P:(DE-Juel1)131720 |b 7 |e Corresponding author |
| 773 | _ | _ | |a 10.1136/bmjopen-2019-034088 |g Vol. 9, no. 12, p. e034088 - |0 PERI:(DE-600)2747269-3 |n 12 |p e034088 - |t Open Heart |v 9 |y 2019 |x 2044-6055 |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/868434/files/Invoice_APC600076223.pdf |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/868434/files/Hensel_2019_BMJ_Open_Intermittent%20theta%20burst%20stimulation%20applied%20during%20early%20rehabilitation%20after%20stroke.pdf |y OpenAccess |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/868434/files/Hensel_2019_BMJ_Open_Intermittent%20theta%20burst%20stimulation%20applied%20during%20early%20rehabilitation%20after%20stroke.pdf?subformat=pdfa |x pdfa |y OpenAccess |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/868434/files/Invoice_APC600076223.pdf?subformat=pdfa |x pdfa |
| 909 | C | O | |o oai:juser.fz-juelich.de:868434 |p openaire |p open_access |p OpenAPC |p driver |p VDB |p openCost |p dnbdelivery |
| 910 | 1 | _ | |a Forschungszentrum Jülich |0 I:(DE-588b)5008462-8 |k FZJ |b 1 |6 P:(DE-Juel1)161406 |
| 910 | 1 | _ | |a Forschungszentrum Jülich |0 I:(DE-588b)5008462-8 |k FZJ |b 2 |6 P:(DE-HGF)0 |
| 910 | 1 | _ | |a INM-3 |0 I:(DE-HGF)0 |b 2 |6 P:(DE-HGF)0 |
| 910 | 1 | _ | |a Forschungszentrum Jülich |0 I:(DE-588b)5008462-8 |k FZJ |b 7 |6 P:(DE-Juel1)131720 |
| 913 | 1 | _ | |a DE-HGF |b Key Technologies |l Decoding the Human Brain |1 G:(DE-HGF)POF3-570 |0 G:(DE-HGF)POF3-572 |2 G:(DE-HGF)POF3-500 |v (Dys-)function and Plasticity |x 0 |4 G:(DE-HGF)POF |3 G:(DE-HGF)POF3 |
| 914 | 1 | _ | |y 2019 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0112 |2 StatID |b Emerging Sources Citation Index |
| 915 | _ | _ | |a Creative Commons Attribution-NonCommercial CC BY-NC 4.0 |0 LIC:(DE-HGF)CCBYNC4 |2 HGFVOC |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0501 |2 StatID |b DOAJ Seal |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0500 |2 StatID |b DOAJ |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0111 |2 StatID |b Science Citation Index Expanded |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |
| 915 | _ | _ | |a IF < 5 |0 StatID:(DE-HGF)9900 |2 StatID |
| 915 | _ | _ | |a OpenAccess |0 StatID:(DE-HGF)0510 |2 StatID |
| 915 | _ | _ | |a Peer Review |0 StatID:(DE-HGF)0030 |2 StatID |b DOAJ : Blind peer review |
| 915 | _ | _ | |a JCR |0 StatID:(DE-HGF)0100 |2 StatID |b BMJ OPEN : 2017 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0310 |2 StatID |b NCBI Molecular Biology Database |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0320 |2 StatID |b PubMed Central |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Clarivate Analytics Master Journal List |
| 920 | _ | _ | |l yes |
| 920 | 1 | _ | |0 I:(DE-Juel1)INM-3-20090406 |k INM-3 |l Kognitive Neurowissenschaften |x 0 |
| 980 | 1 | _ | |a FullTexts |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a I:(DE-Juel1)INM-3-20090406 |
| 980 | _ | _ | |a UNRESTRICTED |
| 980 | _ | _ | |a APC |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|