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@ARTICLE{Galldiks:868438,
      author       = {Galldiks, Norbert and Lohmann, Philipp and Werner,
                      Jan-Michael and Ceccon, Garry and Fink, Gereon R. and
                      Langen, Karl-Josef},
      title        = {{M}olecular imaging and advanced {MRI} findings following
                      immunotherapy in patients with brain tumors},
      journal      = {Expert review of anticancer therapy},
      volume       = {20},
      number       = {1},
      issn         = {1744-8328},
      address      = {Abingdon, Oxon},
      publisher    = {Taylor $\&$ Francis},
      reportid     = {FZJ-2020-00032},
      pages        = {9-15},
      year         = {2020},
      abstract     = {Introduction: Currently, immunotherapy using vaccination
                      strategies or oncolytic virus approaches, cell-based
                      immunotherapy, and the blockade of immune checkpoints are
                      under evaluation in patients with brain cancer. Here we
                      summarize clinically significant imaging findings such as
                      treatment-related changes detected by advanced neuroimaging
                      techniques following the most suitable immunotherapy options
                      currently used in neuro-oncology. We, furthermore, provide
                      an overview of how these advanced imaging techniques may
                      help to overcome shortcomings of standard MRI in the
                      assessment and follow-up of patients with brain cancer.Areas
                      covered: The current literature on neuroimaging for
                      immunotherapy in the field of brain tumors, with a focus on
                      gliomas and brain metastases is summarized.Expert
                      commentary: Data suggest that imaging parameters primarily
                      derived from amino acid PET, diffusion- and
                      perfusion-weighted MRI, or MR spectroscopy are particularly
                      helpful for the evaluation of treatment response and provide
                      valuable information for the differentiation of
                      treatment-induced changes from actual brain tumor
                      progression following various immunotherapy approaches.},
      cin          = {INM-3 / INM-4},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-3-20090406 / I:(DE-Juel1)INM-4-20090406},
      pnm          = {572 - (Dys-)function and Plasticity (POF3-572)},
      pid          = {G:(DE-HGF)POF3-572},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31842635},
      UT           = {WOS:000503931600001},
      doi          = {10.1080/14737140.2020.1705788},
      url          = {https://juser.fz-juelich.de/record/868438},
}