TY  - JOUR
AU  - Langen, Karl-Josef
AU  - Galldiks, Norbert
AU  - Lohmann, Philipp
TI  - Combined FET PET/ADC mapping: improved imaging of glioma infiltration?
JO  - Neuro-Oncology
VL  - 22
IS  - 3
SN  - 1523-5866
CY  - Oxford
PB  - Oxford Univ. Press
M1  - FZJ-2020-00033
SP  - 313-314
PY  - 2020
AB  - Conventional MRI is the method of choice for the diagnosis of cerebral gliomas owing to its ability to detect structural changes with high spatial resolution and outstanding sensitivity. In malignant gliomas, the determination of tumor extent is primarily based on the assessment of blood–brain barrier (BBB) disruption as reflected by contrast enhancement after application of paramagnetic contrast media. In gliomas of World Health Organization (WHO) grades II and III, which are frequently non-enhancing, estimation of tumor extent relies on signal abnormalities in T2-weighted MRI or in the fluid-attenuated inversion recovery (FLAIR) sequence. It is well known, however, that neither contrast enhancement nor FLAIR abnormalities are specific for neoplastic tissue....
LB  - PUB:(DE-HGF)16
C6  - pmid:31859354
UR  - <Go to ISI:>//WOS:000522636300005
DO  - DOI:10.1093/neuonc/noz236
UR  - https://juser.fz-juelich.de/record/868439
ER  -