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@ARTICLE{Smaers:8718,
author = {Smaers, J.B. and Schleicher, A. and Zilles, K. and
Vinicius, L.},
title = {{F}rontal white matter volume is associated with brain
enlargement and higher structural connectivity in anthropoid
primates},
journal = {PLoS one},
volume = {5},
issn = {1932-6203},
address = {Lawrence, Kan.},
publisher = {PLoS},
reportid = {PreJuSER-8718},
pages = {e9123},
year = {2010},
note = {This work was supported by the Cambridge European Trust and
the Leverhulme Trust. JBS is partly funded by the Cambridge
European Trust:
http://www.admin.cam.ac.uk/univ/gsprospectus/funding/overseas/.
LVC is funded by the Leverhulme Trust:
http://www.leverhulme.ac.uk/. The funders had no role in
study design, data collection and analysis, decision to
publish, or preparation of the manuscript.},
abstract = {Previous research has indicated the importance of the
frontal lobe and its 'executive' connections to other brain
structures as crucial in explaining primate neocortical
adaptations. However, a representative sample of volumetric
measurements of frontal connective tissue (white matter) has
not been available. In this study, we present new volumetric
measurements of white and grey matter in the frontal and
non-frontal neocortical lobes from 18 anthropoid species. We
analyze this data in the context of existing theories of
neocortex, frontal lobe and white versus grey matter
hyperscaling. Results indicate that the 'universal scaling
law' of neocortical white to grey matter applies separately
for frontal and non-frontal lobes; that hyperscaling of both
neocortex and frontal lobe to rest of brain is mainly due to
frontal white matter; and that changes in frontal (but not
non-frontal) white matter volume are associated with changes
in rest of brain and basal ganglia, a group of subcortical
nuclei functionally linked to 'executive control'. Results
suggest a central role for frontal white matter in
explaining neocortex and frontal lobe hyperscaling, brain
size variation and higher neural structural connectivity in
anthropoids.},
keywords = {Animals / Basal Ganglia: anatomy $\&$ histology /
Biological Evolution / Brain: anatomy $\&$ histology /
Frontal Lobe: anatomy $\&$ histology / Haplorhini: anatomy
$\&$ histology / Haplorhini: classification / Neocortex:
anatomy $\&$ histology / Species Specificity / J (WoSType)},
cin = {INM-2},
ddc = {500},
cid = {I:(DE-Juel1)INM-2-20090406},
pnm = {Funktion und Dysfunktion des Nervensystems (FUEK409) /
89571 - Connectivity and Activity (POF2-89571)},
pid = {G:(DE-Juel1)FUEK409 / G:(DE-HGF)POF2-89571},
shelfmark = {Biology},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:20161758},
pmc = {pmc:PMC2817750},
UT = {WOS:000274442600021},
doi = {10.1371/journal.pone.0009123},
url = {https://juser.fz-juelich.de/record/8718},
}