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@ARTICLE{Hondrich:872666,
author = {Hondrich, Timm J. J. and Lenyk, Bohdan and Shokoohimehr,
Pegah and Kireev, Dmitry and Maybeck, Vanessa and Mayer,
Dirk and Offenhäusser, Andreas},
title = {{MEA} {R}ecordings and {C}ell–{S}ubstrate
{I}nvestigations with {P}lasmonic and {T}ransparent,
{T}unable {H}oley {G}old},
journal = {ACS applied materials $\&$ interfaces},
volume = {11},
number = {50},
issn = {1944-8252},
address = {Washington, DC},
publisher = {Soc.},
reportid = {FZJ-2020-00157},
pages = {46451 - 46461},
year = {2019},
abstract = {Microelectrode arrays are widely used in different fields
such as neurobiology or biomedicine to read out electrical
signals from cells or biomolecules. One way to improve
microelectrode applications is the development of novel
electrode materials with enhanced or additional
functionality. In this study, we fabricated macroelectrodes
and microelectrode arrays containing gold penetrated by
nanohole arrays as a conductive layer. We used this holey
gold to optically excite surface plasmon polaritons, which
lead to a strong increase in transparency, an effect that is
further enhanced by the plasmon’s interaction with cell
culture medium. By varying the nanohole diameter in
finite-difference time domain simulations, we demonstrate
that the transmission can be increased to above $70\%$ with
its peak at a wavelength depending on the holey gold’s
lattice constant. Further, we demonstrate that the novel
transparent microelectrode arrays are as suitable for
recording cellular electrical activity as standard devices.
Moreover, we prove using spectral measurements and
finite-difference time domain simulations that plasmonically
induced transmission peaks of holey gold red-shift upon
sensing medium or cells in close vicinity (<30 nm) to the
substrate. Thus, we establish plasmonic and transparent
holey gold as a tunable material suitable for cellular
electrical recordings and biosensing applications.},
cin = {ICS-8},
ddc = {600},
cid = {I:(DE-Juel1)ICS-8-20110106},
pnm = {552 - Engineering Cell Function (POF3-552)},
pid = {G:(DE-HGF)POF3-552},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:31752486},
UT = {WOS:000503918300006},
doi = {10.1021/acsami.9b14948},
url = {https://juser.fz-juelich.de/record/872666},
}