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@ARTICLE{Ceccon:872973,
      author       = {Ceccon, Garry and Wollring, Michael and Brunn, Anna and
                      Deckert, Martina and Waldschmidt, Dirk and Fink, Gereon R.
                      and Galldiks, Norbert},
      title        = {{L}eptomeningeal {C}arcinomatosis in a {P}atient with
                      {P}ancreatic {C}ancer {R}esponding to {N}ab-{P}aclitaxel
                      plus {G}emcitabine},
      journal      = {Case reports in oncology},
      volume       = {13},
      issn         = {1662-6575},
      address      = {Basel},
      publisher    = {Karger},
      reportid     = {FZJ-2020-00430},
      pages        = {35 - 42},
      year         = {2020},
      abstract     = {Leptomeningeal carcinomatosis is an extremely rare, but
                      devastating complication in pancreatic cancer patients with
                      a poor prognosis despite multimodal treatment. We present a
                      51-year-old male patient with the very rare condition of
                      leptomeningeal carcinomatosis originating from pancreatic
                      cancer. He presented to our hospital with severe headache
                      and neck stiffness 30 months after systemic chemotherapy.
                      Cerebral and spinal MRI as well as cerebrospinal fluid
                      examination confirmed the diagnosis of leptomeningeal
                      carcinomatosis. The patient responded to gemcitabine plus
                      nab-paclitaxel in terms of elimination of tumor cells from
                      the CSF and concurrent clinical improvement for 3 months.
                      The observed findings suggest that the combination of
                      gemcitabine plus nab-paclitaxel is potentially effective in
                      affected cerebrospinal fluid of pancreatic carcinoma
                      patients.},
      cin          = {INM-3},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-3-20090406},
      pnm          = {572 - (Dys-)function and Plasticity (POF3-572)},
      pid          = {G:(DE-HGF)POF3-572},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:32095126},
      UT           = {WOS:000533875000007},
      doi          = {10.1159/000504697},
      url          = {https://juser.fz-juelich.de/record/872973},
}