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@ARTICLE{Becker:873521,
      author       = {Becker, Johannes and Thies, Tabea and Petry-Schmelzer, Jan
                      Niklas and Dembek, Till A. and Reker, Paul and Mücke, Doris
                      and Grice, Martine and Visser-Vandewalle, Veerle and Fink,
                      Gereon R. and Barbe, Michael},
      title        = {{T}he effects of thalamic and posterior subthalamic deep
                      brain stimulation on speech in patients with essential
                      tremor – {A} prospective, randomized, doubleblind
                      crossover study},
      journal      = {Brain and language},
      volume       = {202},
      issn         = {0093-934X},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {FZJ-2020-00789},
      pages        = {104724 -},
      year         = {2020},
      abstract     = {ObjectiveTo prospectively evaluate the effect of PSA- and
                      VIM DBS on speech in ET patients.MethodsLeads were implanted
                      bilaterally with contacts placed in both VIM and PSA.
                      Thirteen patients were analyzed pre- and postoperatively.
                      Preoperative speech of ET patients was compared to healthy
                      controls. PSA- and VIM-DBS were evaluated in a randomized,
                      double-blind crossover phase.ResultsAt preoperative
                      baseline, we found reduced intelligibility. Differences in
                      acoustic and VAS data (‘ability to speak’) compared to
                      controls were gradient. Articulation rate could be predicted
                      by disease duration. Decreased articulation rate,
                      spirantization and voicing were found for PSA- and VIM-DBS.
                      Targets did not differ in terms of speech
                      deterioration.ConclusionSpeech in ET patients without DBS
                      can be impaired, dependent on patient’s individual
                      characteristics. Both PSA- and VIM-DBS affect speech in a
                      comparable way. Thus, the PSA can be considered an
                      alternative DBS target in ET without higher risk of
                      dysarthria.},
      cin          = {INM-3},
      ddc          = {150},
      cid          = {I:(DE-Juel1)INM-3-20090406},
      pnm          = {572 - (Dys-)function and Plasticity (POF3-572)},
      pid          = {G:(DE-HGF)POF3-572},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31884313},
      UT           = {WOS:000514220400001},
      doi          = {10.1016/j.bandl.2019.104724},
      url          = {https://juser.fz-juelich.de/record/873521},
}