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@ARTICLE{Coleman:873599,
      author       = {Coleman, Jonathan R I and Peyrot, Wouter J and Purves,
                      Kirstin L and Davis, Katrina A S and Rayner, Christopher and
                      Choi, Shing Wan and Hübel, Christopher and Gaspar, Héléna
                      A and Kan, Carol and Van der Auwera, Sandra and Adams, Mark
                      James and Lyall, Donald M and Choi, Karmel W and Consortium,
                      on the behalf of Major Depressive Disorder Working Group of
                      the Psychiatric Genomics and Dunn, Erin C and Vassos,
                      Evangelos and Danese, Andrea and Maughan, Barbara and Grabe,
                      Hans J and Lewis, Cathryn M and O'Reilly, Paul F and
                      McIntosh, Andrew M and Smith, Daniel J and Wray, Naomi R and
                      Hotopf, Matthew and Eley, Thalia C and Breen, Gerome and
                      Wray, Naomi R and Ripke, Stephan and Mattheisen, Manuel and
                      Trzaskowski, Maciej and Byrne, Enda M and Abdellaoui, Abdel
                      and Adams, Mark J and Agerbo, Esben and Air, Tracy M and
                      Andlauer, Till F M and Bacanu, Silviu-Alin and
                      Bækvad-Hansen, Marie and Beekman, Aartjan T F and Bigdeli,
                      Tim B and Binder, Elisabeth B and Bryois, Julien and
                      Buttenschøn, Henriette N and Bybjerg-Grauholm, Jonas and
                      Cai, Na and Castelao, Enrique and Christensen, Jane
                      Hvarregaard and Clarke, Toni-Kim and Coleman, Jonathan R I
                      and Colodro-Conde, Lucía and Couvy-Duchesne, Baptiste and
                      Craddock, Nick and Crawford, Gregory E and Davies, Gail and
                      Deary, Ian J and Degenhardt, Franziska and Derks, Eske M and
                      Direk, Nese and Dolan, Conor V and Dunn, Erin C and Eley,
                      Thalia C and Escott-Price, Valentina and Kiadeh, Farnush
                      Farhadi Hassan and Finucane, Hilary K and Foo, Jerome C and
                      Forstner, Andreas J and Frank, Josef and Gaspar, Héléna A
                      and Gill, Michael and Goes, Fernando S and Gordon, Scott D
                      and Grove, Jakob and Hall, Lynsey S and Hansen, Christine
                      Søholm and Hansen, Thomas F and Herms, Stefan and Hickie,
                      Ian B and Hoffmann, Per and Homuth, Georg and Horn, Carsten
                      and Hottenga, Jouke-Jan and Hougaard, David M and Howard,
                      David M and Ising, Marcus and Jansen, Rick and Jones, Ian
                      and Jones, Lisa A and Jorgenson, Eric and Knowles, James A
                      and Kohane, Isaac S and Kraft, Julia and Kretzschmar, Warren
                      W and Kutalik, Zoltán and Li, Yihan and Lind, Penelope A
                      and MacIntyre, Donald J and MacKinnon, Dean F and Maier,
                      Robert M and Maier, Wolfgang and Marchini, Jonathan and
                      Mbarek, Hamdi and McGrath, Patrick and McGuffin, Peter and
                      Medland, Sarah E and Mehta, Divya and Middeldorp, Christel M
                      and Mihailov, Evelin and Milaneschi, Yuri and Milani, Lili
                      and Mondimore, Francis M and Montgomery, Grant W and
                      Mostafavi, Sara and Mullins, Niamh and Nauck, Matthias and
                      Ng, Bernard and Nivard, Michel G and Nyholt, Dale R and
                      O'Reilly, Paul F and Oskarsson, Hogni and Owen, Michael J
                      and Painter, Jodie N and Pedersen, Carsten Bøcker and
                      Pedersen, Marianne Giørtz and Peterson, Roseann E and
                      Pettersson, Erik and Peyrot, Wouter J and Pistis, Giorgio
                      and Posthuma, Danielle and Quiroz, Jorge A and Qvist, Per
                      and Rice, John P and Riley, Brien P and Rivera, Margarita
                      and Mirza, Saira Saeed and Schoevers, Robert and Schulte,
                      Eva C and Shen, Ling and Shi, Jianxin and Shyn, Stanley I
                      and Sigurdsson, Engilbert and Sinnamon, Grant C B and Smit,
                      Johannes H and Smith, Daniel J and Stefansson, Hreinn and
                      Steinberg, Stacy and Streit, Fabian and Strohmaier, Jana and
                      Tansey, Katherine E and Teismann, Henning and Teumer,
                      Alexander and Thompson, Wesley and Thomson, Pippa A and
                      Thorgeirsson, Thorgeir E and Traylor, Matthew and Treutlein,
                      Jens and Trubetskoy, Vassily and Uitterlinden, Andrés G and
                      Umbricht, Daniel and Van der Auwera, Sandra and van Hemert,
                      Albert M and Viktorin, Alexander and Visscher, Peter M and
                      Wang, Yunpeng and Webb, Bradley T and Weinsheimer, Shantel
                      Marie and Wellmann, Jürgen and Willemsen, Gonneke and Witt,
                      Stephanie H and Wu, Yang and Xi, Hualin S and Yang, Jian and
                      Zhang, Futao and Arolt, Volker and Baune, Bernhard T and
                      Berger, Klaus and Boomsma, Dorret I and Cichon, Sven and
                      Dannlowski, Udo and de Geus, E. J. C. and DePaulo, J Raymond
                      and Domenici, Enrico and Domschke, Katharina and Esko, Tõnu
                      and Grabe, Hans J and Hamilton, Steven P and Hayward,
                      Caroline and Heath, Andrew C and Kendler, Kenneth S and
                      Kloiber, Stefan and Lewis, Glyn and Li, Qingqin S and Lucae,
                      Susanne and Madden, Pamela A F and Magnusson, Patrik K and
                      Martin, Nicholas G and McIntosh, Andrew M and Metspalu,
                      Andres and Mors, Ole and Mortensen, Preben Bo and
                      Müller-Myhsok, Bertram and Nordentoft, Merete and Nöthen,
                      Markus M and O'Donovan, Michael C and Paciga, Sara A and
                      Pedersen, Nancy L and Penninx, Brenda W J H and Perlis, Roy
                      H and Porteous, David J and Potash, James B and Preisig,
                      Martin and Rietschel, Marcella and Schaefer, Catherine and
                      Schulze, Thomas G and Smoller, Jordan W and Stefansson, Kari
                      and Tiemeier, Henning and Uher, Rudolf and Völzke, Henry
                      and Weissman, Myrna M and Werge, Thomas and Lewis, Cathryn M
                      and Levinson, Douglas F and Breen, Gerome and Børglum,
                      Anders D and Sullivan, Patrick F},
      title        = {{C}orrection: {G}enome-wide gene-environment analyses of
                      major depressive disorder and reported lifetime traumatic
                      experiences in {UK} {B}iobank.},
      journal      = {Molecular psychiatry},
      volume       = {25},
      issn         = {1476-5578},
      address      = {London},
      publisher    = {Macmillan},
      reportid     = {FZJ-2020-00842},
      pages        = {1430-1446},
      year         = {2020},
      abstract     = {Depression is more frequent among individuals exposed to
                      traumatic events. Both trauma exposure and depression are
                      heritable. However, the relationship between these traits,
                      including the role of genetic risk factors, is complex and
                      poorly understood. When modelling trauma exposure as an
                      environmental influence on depression, both gene-environment
                      correlations and gene-environment interactions have been
                      observed. The UK Biobank concurrently assessed Major
                      Depressive Disorder (MDD) and self-reported lifetime
                      exposure to traumatic events in 126,522 genotyped
                      individuals of European ancestry. We contrasted genetic
                      influences on MDD stratified by reported trauma exposure
                      (final sample size range: 24,094-92,957). The SNP-based
                      heritability of MDD with reported trauma exposure $(24\%)$
                      was greater than MDD without reported trauma exposure
                      $(12\%).$ Simulations showed that this is not confounded by
                      the strong, positive genetic correlation observed between
                      MDD and reported trauma exposure. We also observed that the
                      genetic correlation between MDD and waist circumference was
                      only significant in individuals reporting trauma exposure
                      (rg = 0.24, p = 1.8 × 10-7 versus
                      rg = -0.05, p = 0.39 in individuals not reporting
                      trauma exposure, difference p = 2.3 × 10-4). Our
                      results suggest that the genetic contribution to MDD is
                      greater when reported trauma is present, and that a complex
                      relationship exists between reported trauma exposure, body
                      composition, and MDD.},
      cin          = {INM-1},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-1-20090406},
      pnm          = {571 - Connectivity and Activity (POF3-571)},
      pid          = {G:(DE-HGF)POF3-571},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31969693},
      UT           = {WOS:000509565100001},
      doi          = {10.1038/s41380-020-0779-4},
      url          = {https://juser.fz-juelich.de/record/873599},
}