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@ARTICLE{Yun:874373,
      author       = {Yun, Seong Dae and Shah, N. J.},
      title        = {{A}nalysis of {EPI} phase correction with low flip‐angle
                      excitation to reduce the required minimum {TE}:
                      {A}pplication to whole‐brain, submillimeter‐resolution
                      f{MRI} at 3 {T}},
      journal      = {Magnetic resonance in medicine},
      volume       = {84},
      number       = {3},
      issn         = {1522-2594},
      address      = {New York, NY [u.a.]},
      publisher    = {Wiley-Liss},
      reportid     = {FZJ-2020-01395},
      pages        = {1416 - 1429},
      year         = {2020},
      abstract     = {Echo planar imaging is used widely for its imaging speed.
                      However, its applications often suffer from ghost artifacts.
                      In the community, an approach using three navigator echoes
                      is used commonly for the artifact correction. Although this
                      scheme is effective, as the matrix size increases for
                      high‐resolution imaging, the navigator echoes can
                      contribute significantly to increasing the “required
                      minimum TE.” To overcome this issue, this work proposes
                      the use of an alternative navigator echo scheme called the
                      “TR‐external” scheme.The TR‐external scheme reduces
                      the required minimum TE by allocating an additional
                      excitation loop for the navigator echoes before every main
                      excitation loop. In this work, a detailed analysis on the
                      TR‐external scheme was performed to assess its performance
                      in comparison to the standard scheme. Visual fMRI was
                      performed to check the feasibility of using the
                      TR‐external scheme for detecting functional signals.The
                      performance of the TR‐external scheme was comparable with
                      that of the standard scheme in terms of the SNR, elimination
                      of ghost artifacts, and the BOLD detection. For a given
                      matrix size (288 × 288), the TR‐external scheme allowed a
                      substantially shorter TE (5.94 ms) compared with the
                      standard scheme, which resulted in a higher SNR.
                      Furthermore, this feature enabled the
                      submillimeter‐resolution (0.73 × 0.73 mm2) fMRI
                      measurement with a favorable TE (35 ms) at 3 T. The fMRI
                      results revealed that activated voxels are well localized
                      along the cortical ribbon.A TR‐external scheme for EPI
                      phase correction was implemented at 3 T. Its feasibility for
                      submillimeter‐resolution fMRI was successfully
                      demonstrated.},
      cin          = {INM-11 / INM-4 / JARA-BRAIN},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-11-20170113 / I:(DE-Juel1)INM-4-20090406 /
                      $I:(DE-82)080010_20140620$},
      pnm          = {573 - Neuroimaging (POF3-573)},
      pid          = {G:(DE-HGF)POF3-573},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:32086847},
      UT           = {WOS:000518150700001},
      doi          = {10.1002/mrm.28218},
      url          = {https://juser.fz-juelich.de/record/874373},
}