TY - JOUR AU - Lohmann, Philipp AU - Kocher, Martin AU - Ruge, Maximillian I. AU - Visser-Vandewalle, Veerle AU - Shah, N. Jon AU - Fink, Gereon R. AU - Langen, Karl-Josef AU - Galldiks, Norbert TI - PET/MRI Radiomics in Patients With Brain Metastases JO - Frontiers in neurology VL - 11 SN - 1664-2295 CY - Lausanne PB - Frontiers Research Foundation M1 - FZJ-2020-01448 SP - 1 PY - 2020 AB - Although a variety of imaging modalities are used or currently being investigated for patients with brain tumors including brain metastases, clinical image interpretation to date uses only a fraction of the underlying complex, high-dimensional digital information from routinely acquired imaging data. The growing availability of high-performance computing allows the extraction of quantitative imaging features from medical images that are usually beyond human perception. Using machine learning techniques and advanced statistical methods, subsets of such imaging features are used to generate mathematical models that represent characteristic signatures related to the underlying tumor biology and might be helpful for the assessment of prognosis or treatment response, or the identification of molecular markers. The identification of appropriate, characteristic image features as well as the generation of predictive or prognostic mathematical models is summarized under the term radiomics. This review summarizes the current status of radiomics in patients with brain metastases. LB - PUB:(DE-HGF)16 C6 - pmid:32116995 UR - <Go to ISI:>//WOS:000517298900001 DO - DOI:10.3389/fneur.2020.00001 UR - https://juser.fz-juelich.de/record/874447 ER -