% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Schweitzer:874452,
      author       = {Schweitzer, F. and Laurent, S. and Fink, G. R. and Barnett,
                      Michael H. and Hartung, H. P. and Warnke, C.},
      title        = {{E}ffects of disease-modifying therapy on peripheral
                      leukocytes in patients with multiple sclerosis},
      journal      = {Journal of neurology},
      volume       = {268},
      number       = {7},
      issn         = {0340-5354},
      address      = {Berlin},
      publisher    = {Springer85301},
      reportid     = {FZJ-2020-01453},
      pages        = {2379-2389},
      year         = {2021},
      abstract     = {Modern disease-modifying therapies (DMTs) in multiple
                      sclerosis (MS) have variable modes of action and selectively
                      suppress or modulate the immune system. In this review, we
                      summarize the predicted and intended as well as unwanted
                      adverse effects on leukocytes in peripheral blood as a
                      result of treatment with DMTs for MS. We link changes in
                      laboratory tests to the possible therapeutic risks that
                      include secondary autoimmunity, infections, and impaired
                      response to vaccinations. Profound knowledge of the intended
                      effects on leukocyte counts, in particular lymphocytes,
                      explained by the mode of action, and adverse effects which
                      may require additional laboratory and clinical vigilance or
                      even drug discontinuation, is needed when prescribing DMTs
                      to treat patients with MS.},
      cin          = {INM-3},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-3-20090406},
      pnm          = {5251 - Multilevel Brain Organization and Variability
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5251},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {32036423},
      UT           = {WOS:000515966700001},
      doi          = {10.1007/s00415-019-09690-6},
      url          = {https://juser.fz-juelich.de/record/874452},
}