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@ARTICLE{Ksbauer:874454,
author = {Käsbauer, Anne-Sophie and Mengotti, Paola and Fink, Gereon
R. and Vossel, Simone},
title = {{R}esting-state {F}unctional {C}onnectivity of the {R}ight
{T}emporoparietal {J}unction {R}elates to {B}elief
{U}pdating and {R}eorienting during {S}patial {A}ttention},
journal = {Journal of cognitive neuroscience},
volume = {32},
number = {6},
issn = {1530-8898},
address = {Cambridge, Mass.},
publisher = {MIT Pr. Journals},
reportid = {FZJ-2020-01455},
pages = {1130-1141},
year = {2020},
abstract = {Although multiple studies characterized the resting-state
functional connectivity (rsFC) of the right temporoparietal
junction (rTPJ), little is known about the link between rTPJ
rsFC and cognitive functions. Given a putative involvement
of rTPJ in both reorienting of attention and the updating of
probabilistic beliefs, this study characterized the
relationship between rsFC of rTPJ with dorsal and ventral
attention systems and these two cognitive processes.
Twenty-three healthy young participants performed a modified
location-cueing paradigm with true and false prior
information about the percentage of cue validity to assess
belief updating and attentional reorienting. Resting-state
fMRI was recorded before and after the task. Seed-based
correlation analysis was employed, and correlations of each
behavioral parameter with rsFC before the task, as well as
with changes in rsFC after the task, were assessed in an
ROI-based approach. Weaker rsFC between rTPJ and right
intraparietal sulcus before the task was associated with
relatively faster updating of the belief that the cue will
be valid after false prior information. Moreover, relatively
faster belief updating, as well as faster reorienting, were
related to an increase in the interhemispheric rsFC between
rTPJ and left TPJ after the task. These findings are in line
with task-based connectivity studies on related attentional
functions and extend results from stroke patients
demonstrating the importance of interhemispheric parietal
interactions for behavioral performance. The present results
not only highlight the essential role of parietal rsFC for
attentional functions but also suggest that cognitive
processing during a task changes connectivity patterns in a
performance-dependent manner.},
cin = {INM-3},
ddc = {610},
cid = {I:(DE-Juel1)INM-3-20090406},
pnm = {572 - (Dys-)function and Plasticity (POF3-572)},
pid = {G:(DE-HGF)POF3-572},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:32027583},
UT = {WOS:000531875200009},
doi = {10.1162/jocn_a_01543},
url = {https://juser.fz-juelich.de/record/874454},
}