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@ARTICLE{Kiesow:874731,
author = {Kiesow, Hannah and Dunbar, Robin I. M. and Kable, Joseph W.
and Kalenscher, Tobias and Vogeley, Kai and Schilbach,
Leonhard and Marquand, Andre F. and Wiecki, Thomas V. and
Bzdok, Danilo},
title = {10,000 social brains: {S}ex differentiation in human brain
anatomy},
journal = {Science advances},
volume = {6},
number = {12},
issn = {2375-2548},
address = {Washington, DC [u.a.]},
publisher = {Assoc.},
reportid = {FZJ-2020-01640},
pages = {eaaz1170 -},
year = {2020},
abstract = {In human and nonhuman primates, sex differences typically
explain much interindividual variability. Male and female
behaviors may have played unique roles in the likely
coevolution of increasing brain volume and more complex
social dynamics. To explore possible divergence in social
brain morphology between men and women living in different
social environments, we applied probabilistic generative
modeling to ~10,000 UK Biobank participants. We observed
strong volume effects especially in the limbic system but
also in regions of the sensory, intermediate, and higher
association networks. Sex-specific brain volume effects in
the limbic system were linked to the frequency and intensity
of social contact, such as indexed by loneliness, household
size, and social support. Across the processing hierarchy of
neural networks, different conditions for social interplay
may resonate in and be influenced by brain anatomy in
sex-dependent ways.},
cin = {INM-3},
ddc = {500},
cid = {I:(DE-Juel1)INM-3-20090406},
pnm = {572 - (Dys-)function and Plasticity (POF3-572)},
pid = {G:(DE-HGF)POF3-572},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:32206722},
UT = {WOS:000521937000033},
doi = {10.1126/sciadv.aaz1170},
url = {https://juser.fz-juelich.de/record/874731},
}