TY  - JOUR
AU  - Amunts, Julia
AU  - Camilleri, Julia
AU  - Eickhoff, Simon B.
AU  - Heim, Stefan
AU  - Weis, Susanne
TI  - Executive functions predict verbal fluency scores in healthy participants
JO  - Scientific reports
VL  - 10
IS  - 1
SN  - 2045-2322
CY  - [London]
PB  - Macmillan Publishers Limited, part of Springer Nature
M1  - FZJ-2020-01869
SP  - 11141
PY  - 2020
AB  - While there is a clear link between impairments of executive functions (EFs), i.e. cognitive control mechanisms that facilitate goal-directed behavior, and speech problems, it is so far unclear exactly which of the complex subdomains of EFs most strongly contribute to speech performance, as measured by verbal fluency (VF) tasks. Furthermore, the impact of intra-individual variability is largely unknown. This study on healthy participants (n = 235) shows that the use of a relevance vector machine approach allows for the prediction of VF performance from EF scores. Based on a comprehensive set of EF scores, results identified cognitive flexibility and inhibition as well as processing speed as strongest predictors for VF performance, but also highlighted a modulatory influence of fluctuating hormone levels. These findings demonstrate that speech production performance is strongly linked to specific EF subdomains, but they also suggest that inter-individual differences should be taken into account.
LB  - PUB:(DE-HGF)16
C6  - pmid:32636406
UR  - <Go to ISI:>//WOS:000562324300014
DO  - DOI:10.1038/s41598-020-65525-9
UR  - https://juser.fz-juelich.de/record/875201
ER  -