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@ARTICLE{Menzel:878136,
author = {Menzel, Miriam and Pereira, Silvania F.},
title = {{C}oherent {F}ourier scatterometry reveals nerve fiber
crossings in the brain},
journal = {Biomedical optics express},
volume = {11},
number = {8},
issn = {2156-7085},
address = {Washington, DC},
publisher = {OSA},
reportid = {FZJ-2020-02654},
pages = {4735 - 4758},
year = {2020},
abstract = {Previous simulation studies by Menzel et al. [Phys. Rev. X
10, 021002 (2020)] have shown that scattering patterns of
light transmitted through artificial nerve fiber
constellations contain valuable information about the tissue
substructure such as the individual fiber orientations in
regions with crossing nerve fibers. Here, we present a
method that measures these scattering patterns in monkey and
human brain tissue using coherent Fourier scatterometry with
normally incident light. By transmitting a non-focused laser
beam (λ = 633 nm) through unstained histological brain
sections, we measure the scattering patterns for small
tissue regions (with diameters of 0.1–1 mm), and show that
they are in accordance with the simulated scattering
patterns. We reveal the individual fiber orientations for up
to three crossing nerve fiber bundles, with crossing angles
down to 25°.},
cin = {INM-1},
ddc = {610},
cid = {I:(DE-Juel1)INM-1-20090406},
pnm = {574 - Theory, modelling and simulation (POF3-574) / HBP
SGA2 - Human Brain Project Specific Grant Agreement 2
(785907) / HBP SGA3 - Human Brain Project Specific Grant
Agreement 3 (945539)},
pid = {G:(DE-HGF)POF3-574 / G:(EU-Grant)785907 /
G:(EU-Grant)945539},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:32923075},
UT = {WOS:000577451600048},
doi = {10.1364/BOE.397604},
url = {https://juser.fz-juelich.de/record/878136},
}