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@ARTICLE{Craig:878512,
author = {Craig, Austin and Kolks, Niklas and Urusova, Elizaveta and
Zischler, Johannes and Brugger, Melanie and Endepols, Heike
and Neumaier, Bernd and Zlatopolskiy, Boris D.},
title = {{P}reparation of labeled aromatic amino acids via
late-stage 18 {F}-fluorination of chiral nickel and copper
complexes},
journal = {Chemical communications},
volume = {56},
number = {66},
issn = {1364-548X},
address = {Cambridge},
publisher = {Soc.},
reportid = {FZJ-2020-02891},
pages = {9505 - 9508},
year = {2020},
abstract = {A general protocol for the preparation of 18F-labeled AAAs
and α-methyl-AAAs applying alcohol-enhanced Cu-mediated
radiofluorination of Bpin-substituted chiral complexes using
Ni/Cu-BPX templates as double protecting groups is reported.
The chiral auxiliaries are easily accessible from
commercially available starting materials in a few synthetic
steps. The versatility of the method was demonstrated by the
high-yielding preparation of a series of [18F]F-AAAs and the
successful implementation of the protocol into automated
radiosynthesis modules.},
cin = {INM-5},
ddc = {540},
cid = {I:(DE-Juel1)INM-5-20090406},
pnm = {573 - Neuroimaging (POF3-573)},
pid = {G:(DE-HGF)POF3-573},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:32686800},
UT = {WOS:000560564400016},
doi = {10.1039/D0CC02223C},
url = {https://juser.fz-juelich.de/record/878512},
}