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@ARTICLE{Otto:878731,
      author       = {Otto, Maike and Wynands, Benedikt and Marienhagen, Jan and
                      Blank, Lars M. and Wierckx, Nick},
      title        = {{B}enzoate {S}ynthesis from {G}lucose or {G}lycerol {U}sing
                      {E}ngineered {P}seudomonas taiwanensis},
      journal      = {Biotechnology journal},
      volume       = {15},
      number       = {11},
      issn         = {1860-7314},
      address      = {Weinheim},
      publisher    = {Wiley-VCH},
      reportid     = {FZJ-2020-03031},
      pages        = {2000211 -},
      year         = {2020},
      note         = {weitere Grants: German Research Foundation (DFG) through
                      the Emmy Noether program (WI 4255/1‐1) German Federal
                      Ministry of Education and Research (BMBF) through the
                      NO‐STRESS project (FKZ 031B0852A)},
      abstract     = {Benzoic acid is one of the most commonly used food
                      preservatives, but currently exclusively produced in
                      petrochemical processes. In this study, a bio‐based
                      production pathway using an engineered strain of Pseudomonas
                      taiwanensis is described. In a phenylalanine‐overproducing
                      strain, bacterial and plant genes are heterologously
                      expressed to achieve production of benzoate via a
                      β‐oxidation pathway. Strategic disruption of the native
                      Pseudomonas benzoate degradation pathway further allows the
                      production of catechol and cis,cis‐muconate. Taken
                      together, this work demonstrates new routes for the
                      microbial production of these industrially relevant
                      chemicals from renewable resources.},
      cin          = {IBG-1},
      ddc          = {570},
      cid          = {I:(DE-Juel1)IBG-1-20101118},
      pnm          = {581 - Biotechnology (POF3-581) / DFG project 390919832 -
                      EXC 2186: Das Fuel Science Center – Adaptive
                      Umwandlungssysteme für erneuerbare Energie- und
                      Kohlenstoffquellen (390919832)},
      pid          = {G:(DE-HGF)POF3-581 / G:(GEPRIS)390919832},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:32721071},
      UT           = {WOS:000567363700001},
      doi          = {10.1002/biot.202000211},
      url          = {https://juser.fz-juelich.de/record/878731},
}