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@ARTICLE{Taubert:8807,
author = {Taubert, M. and Dafotakis, M. and Sparing, R. and Eickhoff,
S. B. and Leuchte, S. and Fink, G. R. and Nowak, D. A.},
title = {{I}nhibition of the anterior intraparietal area and the
dorsal premotor cortex interfere with arbitrary visuo-motor
mapping},
journal = {Clinical neurophysiology},
volume = {121},
issn = {1388-2457},
address = {Amsterdam [u.a.]},
publisher = {Elsevier Science},
reportid = {PreJuSER-8807},
pages = {408 - 413},
year = {2010},
note = {The present project was supported by the "Arbeitskreis
Botulinumtoxin" of the Deutsche Gesellschaft fur Neurologie
(DGN).},
abstract = {The contribution of the human anterior intraparietal area
and the dorsal premotor cortex to arbitrary visuo-motor
mapping during grasping were tested.Trained right-handed
subjects reached for and pincer-grasped a cube with the
right hand in the absence of visual feedback after the cube
location had been displayed for 200ms. During the reaching
movements, the colour of the cube changed and visual
feedback about the change of colour was provided for 100ms
at 500ms after movement onset (at the time of peak grasp
aperture). Depending on colour, subjects were instructed to
either pincer-grasp the cube in a horizontal or vertical
grasp position with the latter necessitating wrist rotation
(experiment 1) or to pincer-grasp and transport the cube to
either a left or right target position (experiment 2).
Within two consecutive 200ms time windows (TMS 1 and 2)
starting 500ms and 700ms after movement onset, respectively,
double pulses of supra-threshold transcranial magnetic
stimulation (inter-stimulus interval: 100ms) were delivered
over (i) the left primary motor cortex (90 degrees
vertically angulated coil position, control stimulation),
(ii) the left dorsal premotor cortex or (ii) the left
anterior intraparietal area.Compared to control stimulation,
stimulation of the anterior intraparietal area, but not of
the dorsal premotor cortex, at TMS 1 delayed the times to
wrist rotation (experiment 1) and hand transport (experiment
2). Compared to control stimulation, stimulation of the
dorsal premotor cortex, but not of the anterior
intraparietal area, at TMS 2 delayed both wrist rotation
(experiment 1) and hand transport (experiment 2).We contend
that the anterior intraparietal area and the dorsal premotor
cortex are both involved albeit at different phases during
the mapping of arbitrary visual cues with goal directed
grasp and transport movements.These data add to the current
understanding of how human cortical areas work in concert
during manual activities.},
keywords = {Adult / Biofeedback, Psychology: physiology / Biomechanics
/ Brain Mapping / Cues / Evoked Potentials, Motor:
physiology / Executive Function: physiology / Frontal Lobe:
anatomy $\&$ histology / Frontal Lobe: physiology /
Functional Laterality: physiology / Hand Strength:
physiology / Humans / Magnetic Resonance Imaging / Motor
Cortex: anatomy $\&$ histology / Motor Cortex: physiology /
Neural Inhibition: physiology / Neuropsychological Tests /
Parietal Lobe: anatomy $\&$ histology / Parietal Lobe:
physiology / Photic Stimulation / Psychomotor Performance:
physiology / Range of Motion, Articular: physiology /
Reaction Time: physiology / Transcranial Magnetic
Stimulation / Wrist: physiology / J (WoSType)},
cin = {INM-2 / INM-3 / JARA-BRAIN},
ddc = {610},
cid = {I:(DE-Juel1)INM-2-20090406 / I:(DE-Juel1)INM-3-20090406 /
$I:(DE-82)080010_20140620$},
pnm = {Funktion und Dysfunktion des Nervensystems (FUEK409) /
89572 - (Dys-)function and Plasticity (POF2-89572)},
pid = {G:(DE-Juel1)FUEK409 / G:(DE-HGF)POF2-89572},
shelfmark = {Clinical Neurology / Neurosciences},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:20004613},
UT = {WOS:000274557800022},
doi = {10.1016/j.clinph.2009.11.011},
url = {https://juser.fz-juelich.de/record/8807},
}