TY  - JOUR
AU  - Gulban, Omer Faruk
AU  - Goebel, Rainer
AU  - Moerel, Michelle
AU  - Zachlod, Daniel
AU  - Mohlberg, Hartmut
AU  - Amunts, Katrin
AU  - de Martino, Federico
TI  - Improving a probabilistic cytoarchitectonic atlas of auditory cortex using a novel method for inter-individual alignment
JO  - eLife
VL  - 9
SN  - 2050-084X
CY  - Cambridge
PB  - eLife Sciences Publications
M1  - FZJ-2020-03120
SP  - e56963
PY  - 2020
AB  - The human superior temporal plane, the site of the auditory cortex, displays high inter-individual macro-anatomical variation. This questions the validity of curvature-based alignment (CBA) methods for in vivo imaging data. Here, we have addressed this issue by developing CBA+, which is a cortical surface registration method that uses prior macro-anatomical knowledge. We validate this method by using cytoarchitectonic areas on 10 individual brains (which we make publicly available). Compared to volumetric and standard surface registration, CBA+ results in a more accurate cytoarchitectonic auditory atlas. The improved correspondence of micro-anatomy following the improved alignment of macro-anatomy validates the superiority of CBA+ compared to CBA. In addition, we use CBA+ to align in vivo and postmortem data. This allows projection of functional and anatomical information collected in vivo onto the cytoarchitectonic areas, which has the potential to contribute to the ongoing debate on the parcellation of the human auditory cortex.
LB  - PUB:(DE-HGF)16
C6  - pmid:32755545
UR  - <Go to ISI:>//WOS:000558758100001
DO  - DOI:10.7554/eLife.56963
UR  - https://juser.fz-juelich.de/record/884207
ER  -