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@ARTICLE{Hardy:884729,
author = {Hardy, Aël and Sharma, Vikas and Kever, Larissa and
Frunzke, Julia},
title = {{G}enome sequence and characterization of five
bacteriophagesinfecting {S}treptomyces coelicolor and
{S}treptomyces venezuelae: {A}lderaan, {C}oruscant,
{D}agobah, {E}ndor1 and {E}ndor2},
journal = {Viruses},
volume = {12},
number = {10},
issn = {1999-4915},
address = {Basel},
publisher = {MDPI},
reportid = {FZJ-2020-03223},
pages = {1065 -},
year = {2020},
abstract = {Streptomyces are well-known antibiotic producers, also
characterized by a complex morphological differentiation.
Streptomyces, like all bacteria, are confronted with the
constant threat of phage predation, which in turn shapes
bacterial evolution. However, despite significant sequencing
efforts recently, relatively few phages infecting
Streptomyces have been characterized compared to other
genera. Here, we present the isolation and characterization
of five novel Streptomyces phages. All five phages belong to
the Siphoviridae family, based on their morphology as
determined by transmission electron microscopy. Genome
sequencing and life style predictions suggested that four of
them were temperate phages, while one had a lytic lifestyle.
Moreover, one of the newly sequenced phages shows very
little homology to already described phages, highlighting
the still largely untapped viral diversity. Altogether, this
study expands the number of characterized phages of
Streptomyces and sheds light on phage evolution and
phage-host dynamics in Streptomyces.},
cin = {IBG-1},
ddc = {050},
cid = {I:(DE-Juel1)IBG-1-20101118},
pnm = {581 - Biotechnology (POF3-581)},
pid = {G:(DE-HGF)POF3-581},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:32977693},
UT = {WOS:000587007800001},
doi = {10.3390/v12101065},
url = {https://juser.fz-juelich.de/record/884729},
}