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@ARTICLE{Li:884810,
      author       = {Li, Ting and Wang, Ling and Camilleri, Julia and Chen,
                      Xinling and Li, Suiqing and Stewart, Jennifer L. and Jiang,
                      Yali and Eickhoff, Simon B. and Feng, Chunliang},
      title        = {{M}apping common grey matter volume deviation across child
                      and adolescent psychiatric disorders},
      journal      = {Neuroscience $\&$ biobehavioral reviews},
      volume       = {115},
      issn         = {0149-7634},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {FZJ-2020-03267},
      pages        = {273 - 284},
      year         = {2020},
      abstract     = {Childhood and adolescence represent a time notable for the
                      emergence of many psychiatric disorders, where comorbidity
                      and co-occurrence of symptoms are well-documented. However,
                      it remains unclear whether there exists common brain
                      structural disturbance across psychiatric disorders in
                      youth. Here, we conduct a transdiagnostic meta-analysis of
                      132 structural neuroimaging experiments in youth consisting
                      of multiple psychiatric diagnoses. Compared to healthy
                      peers, youth psychiatric disorders are characterized by
                      reduced grey matter volume (GMV) of amygdala and lateral
                      orbitofrontal cortex and enhanced GMV of ventromedial
                      prefrontal cortex and precuneus. These four regions were
                      then subjected to functional connectivity and decoding
                      analyses based on healthy participant datasets, allowing for
                      a data-driven quantitative inference on psychophysiological
                      functions. These regions and their networks mapped onto
                      systems implicated in negative valence, positive valence, as
                      well as social and cognitive functioning. Together, our
                      findings are consistent with transdiagnostic models of
                      psychopathology, uncovering common structural disturbance
                      across youth psychiatric disorders, potentially reflecting
                      an intermediate transdiagnostic phenotype in association
                      with broad dimensions of youth psychopathology.},
      cin          = {INM-7},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-7-20090406},
      pnm          = {572 - (Dys-)function and Plasticity (POF3-572)},
      pid          = {G:(DE-HGF)POF3-572},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:32485265},
      UT           = {WOS:000579731200022},
      doi          = {10.1016/j.neubiorev.2020.05.015},
      url          = {https://juser.fz-juelich.de/record/884810},
}