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@ARTICLE{Grigoriev:885389,
author = {Grigoriev, S. V. and Iashina, E. G. and Bairamukov, V. Yu.
and Pipich, Vitaliy and Radulescu, Aurel and Filatov, M. V.
and Pantina, R. A. and Varfolomeeva, E. Yu.},
title = {{S}witch of fractal properties of {DNA} in chicken
erythrocytes nuclei by mechanical stress},
journal = {Physical review / E},
volume = {102},
number = {3},
issn = {2470-0045},
address = {Woodbury, NY},
publisher = {Inst.},
reportid = {FZJ-2020-03786},
pages = {032415},
year = {2020},
abstract = {The small-angle neutron scattering (SANS) on the chicken
erythrocyte nuclei demonstrates the bifractal nature of the
chromatin structural organization. Use of the contrast
variation (D2O−H2O) in SANS measurements reveals the
differences in the DNA and protein arrangements inside the
chromatin substance. It is the DNA that serves as a
framework that constitutes the bifractal behavior showing
the mass fractal properties with D=2.22 at a smaller scale
and the logarithmic fractal behavior with D≈3 at a larger
scale. The protein spatial organization shows the mass
fractal properties with D≈2.34 throughout the whole
nucleus. The borderline between two fractal levels can be
significantly shifted toward smaller scales by
centrifugation of the nuclei disposed on the dry substrate,
since nuclei suffer from mechanical stress transforming them
to a disklike shape. The height of this disk measured by
atomic force microscopy (AFM) coincides closely with the
fractal borderline, thus characterizing two types of the
chromatin with the soft (at larger scale) and rigid (at
smaller scale) properties. The combined SANS and AFM
measurements demonstrate the stress induced switch of the
DNA fractal properties from the rigid, but loosely packed,
mass fractal to the soft, but densely packed, logarithmic
fractal.},
cin = {JCNS-FRM-II / JCNS-1 / MLZ},
ddc = {530},
cid = {I:(DE-Juel1)JCNS-FRM-II-20110218 /
I:(DE-Juel1)JCNS-1-20110106 / I:(DE-588b)4597118-3},
pnm = {6G4 - Jülich Centre for Neutron Research (JCNS) (POF3-623)
/ 6G15 - FRM II / MLZ (POF3-6G15)},
pid = {G:(DE-HGF)POF3-6G4 / G:(DE-HGF)POF3-6G15},
experiment = {EXP:(DE-MLZ)KWS2-20140101 / EXP:(DE-MLZ)KWS3-20140101},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:33075965},
UT = {WOS:000579013900009},
doi = {10.1103/PhysRevE.102.032415},
url = {https://juser.fz-juelich.de/record/885389},
}