000885450 001__ 885450
000885450 005__ 20210130010410.0
000885450 0247_ $$2doi$$a10.1016/j.jbiotec.2020.09.016
000885450 0247_ $$2ISSN$$a0168-1656
000885450 0247_ $$2ISSN$$a1873-4863
000885450 0247_ $$2Handle$$a2128/26006
000885450 0247_ $$2pmid$$a32976868
000885450 0247_ $$2WOS$$aWOS:000600955400007
000885450 037__ $$aFZJ-2020-03833
000885450 082__ $$a540
000885450 1001_ $$0P:(DE-Juel1)157953$$aMuschallik, Lukas$$b0
000885450 245__ $$aSynthesis of α-hydroxy ketones and vicinal diols with the Bacillus licheniformis DSM 13T butane-2,3-diol dehydrogenase
000885450 260__ $$aAmsterdam [u.a.]$$bElsevier Science$$c2020
000885450 3367_ $$2DRIVER$$aarticle
000885450 3367_ $$2DataCite$$aOutput Types/Journal article
000885450 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1604299814_23528
000885450 3367_ $$2BibTeX$$aARTICLE
000885450 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000885450 3367_ $$00$$2EndNote$$aJournal Article
000885450 520__ $$aThe enantioselective synthesis of α-hydroxy ketones and vicinal diols is an intriguing field because of the broad applicability of these molecules. Although, butandiol dehydrogenases are known to play a key role in the production of 2,3-butandiol, their potential as biocatalysts is still not well studied. Here, we investigate the biocatalytic properties of the meso-butanediol dehydrogenase from Bacillus licheniformis DSM 13T (BlBDH). The encoding gene was cloned with an N-terminal StrepII-tag and recombinantly overexpressed in E. coli. BlBDH is highly active towards several non-physiological diketones and α-hydroxyketones with varying aliphatic chain lengths or even containing phenyl moieties. By adjusting the reaction parameters in biotransformations the formation of either the α-hydroxyketone intermediate or the diol can be controlled.
000885450 536__ $$0G:(DE-HGF)POF3-581$$a581 - Biotechnology (POF3-581)$$cPOF3-581$$fPOF III$$x0
000885450 588__ $$aDataset connected to CrossRef
000885450 7001_ $$0P:(DE-HGF)0$$aKipp, Carina Ronja$$b1
000885450 7001_ $$0P:(DE-HGF)0$$aRecker, Inga$$b2
000885450 7001_ $$0P:(DE-HGF)0$$aBongaerts, Johannes$$b3
000885450 7001_ $$0P:(DE-Juel1)131522$$aPohl, Martina$$b4
000885450 7001_ $$0P:(DE-HGF)0$$aGellissen, Melanie$$b5
000885450 7001_ $$0P:(DE-Juel1)128727$$aSchöning, Michael J.$$b6
000885450 7001_ $$0P:(DE-HGF)0$$aSelmer, Thorsten$$b7
000885450 7001_ $$0P:(DE-HGF)0$$aSiegert, Petra$$b8$$eCorresponding author
000885450 773__ $$0PERI:(DE-600)2016476-2$$a10.1016/j.jbiotec.2020.09.016$$gVol. 324, p. 61 - 70$$p61 - 70$$tJournal of biotechnology$$v324$$x0168-1656$$y2020
000885450 8564_ $$uhttps://juser.fz-juelich.de/record/885450/files/Muschallik%20et%20all%20JBIOTEC-S-20-01483.pdf$$yPublished on 2020-09-22. Available in OpenAccess from 2021-09-22.
000885450 8564_ $$uhttps://juser.fz-juelich.de/record/885450/files/Muschallik%20et%20all%20JBIOTEC-S-20-01483.pdf?subformat=pdfa$$xpdfa$$yPublished on 2020-09-22. Available in OpenAccess from 2021-09-22.
000885450 909CO $$ooai:juser.fz-juelich.de:885450$$pdnbdelivery$$pdriver$$pVDB$$popen_access$$popenaire
000885450 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)157953$$aForschungszentrum Jülich$$b0$$kFZJ
000885450 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131522$$aForschungszentrum Jülich$$b4$$kFZJ
000885450 9131_ $$0G:(DE-HGF)POF3-581$$1G:(DE-HGF)POF3-580$$2G:(DE-HGF)POF3-500$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bKey Technologies$$lKey Technologies for the Bioeconomy$$vBiotechnology$$x0
000885450 9141_ $$y2020
000885450 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2019-12-21
000885450 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2019-12-21
000885450 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2019-12-21
000885450 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2019-12-21
000885450 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2019-12-21
000885450 915__ $$0LIC:(DE-HGF)CCBYNCND4$$2HGFVOC$$aCreative Commons Attribution-NonCommercial-NoDerivs CC BY-NC-ND 4.0
000885450 915__ $$0StatID:(DE-HGF)0530$$2StatID$$aEmbargoed OpenAccess
000885450 915__ $$0StatID:(DE-HGF)1060$$2StatID$$aDBCoverage$$bCurrent Contents - Agriculture, Biology and Environmental Sciences$$d2019-12-21
000885450 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2019-12-21
000885450 915__ $$0StatID:(DE-HGF)0110$$2StatID$$aWoS$$bScience Citation Index$$d2019-12-21
000885450 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2019-12-21
000885450 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5$$d2019-12-21
000885450 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2019-12-21
000885450 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bJ BIOTECHNOL : 2018$$d2019-12-21
000885450 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database$$d2019-12-21
000885450 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2019-12-21
000885450 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2019-12-21
000885450 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz$$d2019-12-21$$wger
000885450 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2019-12-21
000885450 9201_ $$0I:(DE-Juel1)IBG-1-20101118$$kIBG-1$$lBiotechnologie$$x0
000885450 980__ $$ajournal
000885450 980__ $$aVDB
000885450 980__ $$aUNRESTRICTED
000885450 980__ $$aI:(DE-Juel1)IBG-1-20101118
000885450 9801_ $$aFullTexts