TY  - JOUR
AU  - Abuayyash, Adham
AU  - Ziegler, Nadine
AU  - Meyer, Hajo
AU  - Meischein, Michael
AU  - Sengstock, Christina
AU  - Moellenhoff, Julian
AU  - Rurainsky, Christian
AU  - Heggen, Marc
AU  - Garzón-Manjón, Alba
AU  - Scheu, Christina
AU  - Tschulik, Kristina
AU  - Ludwig, Alfred
AU  - Köller, Manfred
TI  - Enhanced antibacterial performance of ultrathin silver/platinum nanopatches by a sacrificial anode mechanism
JO  - Nanomedicine / Nanotechnology, biology and medicine
VL  - 24
SN  - 1549-9634
CY  - New York, NY
PB  - Elsevier
M1  - FZJ-2020-03898
SP  - 102126 -
PY  - 2020
AB  - The development of antibacterial implant surfaces is a challenging task in biomaterial research. We fabricated a highly antibacterial bimetallic platinum (Pt)/silver(Ag) nanopatch surface by short time sputtering of Pt and Ag on titanium. The sputter process led to a patch-like distribution with crystalline areas in the nanometer-size range (1.3–3.9 nm thickness, 3–60 nm extension). Structural analyses of Pt/Ag samples showed Ag- and Pt-rich areas containing nanoparticle-like Pt deposits of 1–2 nm. The adhesion and proliferation properties of S. aureus on the nanopatch samples were analyzed. Consecutively sputtered Ag/Pt nanopatches (Pt followed by Ag) induced enhanced antimicrobial activity compared to co-sputtered Pt/Ag samples or pure Ag patches of similar Ag amounts. The underlying sacrificial anode mechanism was proved by linear sweep voltammetry. The advantages of this nanopatch coating are the enhanced antimicrobial activity despite a reduced total amount of Ag/Pt and a self-limited effect due the rapid Ag dissolution.
LB  - PUB:(DE-HGF)16
C6  - pmid:31734515
UR  - <Go to ISI:>//WOS:000521829800021
DO  - DOI:10.1016/j.nano.2019.102126
UR  - https://juser.fz-juelich.de/record/885518
ER  -