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@ARTICLE{Schwanemann:885823,
author = {Schwanemann, Tobias and Otto, Maike and Wierckx, Nick and
Wynands, Benedikt},
title = {{P}seudomonas as {V}ersatile {A}romatics {C}ell {F}actory},
journal = {Biotechnology journal},
volume = {15},
number = {11},
issn = {1860-7314},
address = {Weinheim},
publisher = {Wiley-VCH},
reportid = {FZJ-2020-04114},
pages = {1900569},
year = {2020},
note = {Biotechnologie 1},
abstract = {Aromatics and their derivatives are valuable chemicals with
a plethora of important applications and thus play an
integral role in modern society. Their current production
relies mostly on the exploitation of petroleum resources.
Independency from dwindling fossil resources and rising
environmental concerns are major driving forces for the
transition towards the production of sustainable aromatics
from renewable feedstocks or waste streams. Whole‐cell
biocatalysis is a promising strategy that allows the
valorization of highly abundant, low‐cost substrates. In
the last decades, extensive efforts are undertaken to allow
the production of a wide spectrum of different aromatics and
derivatives using microbes as biocatalysts. Pseudomonads are
intriguing hosts for biocatalysis, as they display unique
characteristics beneficial for the production of aromatics,
including a distinct tolerance and versatile metabolism.This
review highlights biotechnological applications of
Pseudomonas as host for the production of aromatics and
derived compounds. This includes their de novo biosynthesis
from renewable resources, biotransformations in single‐
and biphasic fermentation setups, metabolic funneling of
lignin‐derived aromatics, and the upcycling of aromatic
monomers from plastic waste streams. Additionally, this
review provides insights into unique features of
Pseudomonads that make them exceptional hosts for aromatics
biotechnology and discusses engineering strategies.},
cin = {IBG-1},
ddc = {570},
cid = {I:(DE-Juel1)IBG-1-20101118},
pnm = {581 - Biotechnology (POF3-581)},
pid = {G:(DE-HGF)POF3-581},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:32978889},
UT = {WOS:000579460900001},
doi = {10.1002/biot.201900569},
url = {https://juser.fz-juelich.de/record/885823},
}