TY  - JOUR
AU  - Novak, Sanja
AU  - Zhang, Jing
AU  - Kentzinger, Emmanuel
AU  - Rücker, Ulrich
AU  - Portale, Giuseppe
AU  - Jung, Niklas
AU  - Jonas, Ulrich
AU  - Myung, Jin S.
AU  - Winkler, Roland G.
AU  - Gompper, Gerhard
AU  - Dhont, Jan K. G.
AU  - Stiakakis, Emmanuel
TI  - DNA Self-Assembly Mediated by Programmable Soft-Patchy Interactions
JO  - ACS nano
VL  - 14
IS  - 10
SN  - 1936-086X
CY  - Washington, DC
PB  - Soc.
M1  - FZJ-2020-04162
SP  - 13524–13535
PY  - 2020
AB  - Adding shape and interaction anisotropy to a colloidal particle offers exquisitely tunable routes to engineer a rich assortment of complex-architected structures. Inspired by the hierarchical self-assembly concept with block copolymers and DNA liquid crystals and exploiting the unique assembly properties of DNA, we report here the construction and self-assembly of DNA-based soft-patchy anisotropic particles with a high degree of modularity in the system’s design. By programmable positioning of thermoresponsive polymeric patches on the backbone of a stiff DNA duplex with linear and star-shaped architecture, we reversibly drive the DNA from a disordered ensemble to a diverse array of long-range ordered multidimensional nanostructures with tunable lattice spacing, ranging from lamellar to bicontinuous double-gyroid and double-diamond cubic morphologies, through the alteration of temperature. Our results demonstrate that the proposed hierarchical self-assembly strategy can be applied to any kind of DNA nanoarchitecture, highlighting the design principles for integration of self-assembly concepts from the physics of liquid crystals, block copolymers, and patchy colloids into the continuously growing interdisciplinary research field of structural DNA nanotechnology.
LB  - PUB:(DE-HGF)16
C6  - 33048544
UR  - <Go to ISI:>//WOS:000586793400100
DO  - DOI:10.1021/acsnano.0c05536
UR  - https://juser.fz-juelich.de/record/885886
ER  -