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@ARTICLE{Hofer:885965,
      author       = {Hofer, Edith and Roshchupkin, Gennady V. and Adams, Hieab
                      H. H. and Knol, Maria J. and Lin, Honghuang and Li, Shuo and
                      Zare, Habil and Ahmad, Shahzad and Armstrong, Nicola J. and
                      Satizabal, Claudia L. and Bernard, Manon and Bis, Joshua C.
                      and Gillespie, Nathan A. and Luciano, Michelle and Mishra,
                      Aniket and Scholz, Markus and Teumer, Alexander and Xia, Rui
                      and Jian, Xueqiu and Mosley, Thomas H. and Saba, Yasaman and
                      Pirpamer, Lukas and Seiler, Stephan and Becker, James T. and
                      Carmichael, Owen and Rotter, Jerome I. and Psaty, Bruce M.
                      and Lopez, Oscar L. and Amin, Najaf and van der Lee, Sven J.
                      and Yang, Qiong and Himali, Jayandra J. and Maillard,
                      Pauline and Beiser, Alexa S. and DeCarli, Charles and
                      Karama, Sherif and Lewis, Lindsay and Harris, Mat and
                      Bastin, Mark E. and Deary, Ian J. and Veronica Witte, A. and
                      Beyer, Frauke and Loeffler, Markus and Mather, Karen A. and
                      Schofield, Peter R. and Thalamuthu, Anbupalam and Kwok, John
                      B. and Wright, Margaret J. and Ames, David and Trollor,
                      Julian and Jiang, Jiyang and Brodaty, Henry and Wen, Wei and
                      Vernooij, Meike W. and Hofman, Albert and Uitterlinden,
                      André G. and Niessen, Wiro J. and Wittfeld, Katharina and
                      Bülow, Robin and Völker, Uwe and Pausova, Zdenka and Bruce
                      Pike, G. and Maingault, Sophie and Crivello, Fabrice and
                      Tzourio, Christophe and Amouyel, Philippe and Mazoyer,
                      Bernard and Neale, Michael C. and Franz, Carol E. and Lyons,
                      Michael J. and Panizzon, Matthew S. and Andreassen, Ole A.
                      and Dale, Anders M. and Logue, Mark and Grasby, Katrina L.
                      and Jahanshad, Neda and Painter, Jodie N. and Colodro-Conde,
                      Lucía and Bralten, Janita and Hibar, Derrek P. and Lind,
                      Penelope A. and Pizzagalli, Fabrizio and Stein, Jason L. and
                      Thompson, Paul M. and Medland, Sarah E. and Sachdev,
                      Perminder S. and Kremen, William S. and Wardlaw, Joanna M.
                      and Villringer, Arno and van Duijn, Cornelia M. and Grabe,
                      Hans J. and Longstreth, William T. and Fornage, Myriam and
                      Paus, Tomas and Debette, Stephanie and Arfan Ikram, M. and
                      Schmidt, Helena and Schmidt, Reinhold and Seshadri, Sudha},
      collaboration = {consortium, ENIGMA and Caspers, Svenja},
      title        = {{G}enetic correlations and genome-wide associations of
                      cortical structure in general population samples of 22,824
                      adults},
      journal      = {Nature Communications},
      volume       = {11},
      number       = {1},
      issn         = {2041-1723},
      address      = {[London]},
      publisher    = {Nature Publishing Group UK},
      reportid     = {FZJ-2020-04196},
      pages        = {4796},
      year         = {2020},
      abstract     = {Cortical thickness, surface area and volumes vary with age
                      and cognitive function, and in neurological and psychiatric
                      diseases. Here we report heritability, genetic correlations
                      and genome-wide associations of these cortical measures
                      across the whole cortex, and in 34 anatomically predefined
                      regions. Our discovery sample comprises 22,824 individuals
                      from 20 cohorts within the Cohorts for Heart and Aging
                      Research in Genomic Epidemiology (CHARGE) consortium and the
                      UK Biobank. We identify genetic heterogeneity between
                      cortical measures and brain regions, and 160 genome-wide
                      significant associations pointing to wnt/β-catenin, TGF-β
                      and sonic hedgehog pathways. There is enrichment for genes
                      involved in anthropometric traits, hindbrain development,
                      vascular and neurodegenerative disease and psychiatric
                      conditions. These data are a rich resource for studies of
                      the biological mechanisms behind cortical development and
                      aging.},
      cin          = {INM-1},
      ddc          = {500},
      cid          = {I:(DE-Juel1)INM-1-20090406},
      pnm          = {571 - Connectivity and Activity (POF3-571)},
      pid          = {G:(DE-HGF)POF3-571},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:32963231},
      UT           = {WOS:000573752500003},
      doi          = {10.1038/s41467-020-18367-y},
      url          = {https://juser.fz-juelich.de/record/885965},
}